Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Metabotropic glutamate receptor 3
(Homo sapiens (Human)) | BDBM290560
(US10099993, Compound 141)Show SMILES Cc1c(O)c(ccc1OCc1cccc(c1)-c1ccc(C(O)=O)c(Cl)c1)C(=O)CC(C)(C)C Show InChI InChI=1S/C27H27ClO5/c1-16-24(11-10-21(25(16)30)23(29)14-27(2,3)4)33-15-17-6-5-7-18(12-17)19-8-9-20(26(31)32)22(28)13-19/h5-13,30H,14-15H2,1-4H3,(H,31,32) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | n/a | n/a | 656 | n/a | n/a | n/a | n/a |
SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE
US Patent
| |
US Patent US10099993 (2018)
BindingDB Entry DOI: 10.7270/Q2Z89FFP |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 2
(Homo sapiens (Human)) | BDBM290560
(US10099993, Compound 141)Show SMILES Cc1c(O)c(ccc1OCc1cccc(c1)-c1ccc(C(O)=O)c(Cl)c1)C(=O)CC(C)(C)C Show InChI InChI=1S/C27H27ClO5/c1-16-24(11-10-21(25(16)30)23(29)14-27(2,3)4)33-15-17-6-5-7-18(12-17)19-8-9-20(26(31)32)22(28)13-19/h5-13,30H,14-15H2,1-4H3,(H,31,32) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | n/a | n/a | 391 | n/a | n/a | 7.3 | 25 |
SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE
US Patent
| Assay Description
Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (... |
US Patent US10099993 (2018)
BindingDB Entry DOI: 10.7270/Q2Z89FFP |
More data for this
Ligand-Target Pair | |