Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Programmed cell death 1 ligand 1
(Homo sapiens (Human)) | BDBM482520
(US10919852, Compound TABLE 1.219 | US11708326, Com...)Show SMILES Cc1c(OCCCN2CCC(F)CC2)cccc1-c1cccc2[C@H](CCc12)Oc1cc(OCc2cc(cc(c2)C#N)C#N)c(CN2CCC3(C2)NC(=O)NC3=O)cc1Cl |r| Show InChI InChI=1S/C46H46ClFN6O5/c1-29-35(5-3-8-40(29)57-18-4-14-53-15-11-34(48)12-16-53)36-6-2-7-38-37(36)9-10-41(38)59-43-23-42(58-27-32-20-30(24-49)19-31(21-32)25-50)33(22-39(43)47)26-54-17-13-46(28-54)44(55)51-45(56)52-46/h2-3,5-8,19-23,34,41H,4,9-18,26-28H2,1H3,(H2,51,52,55,56)/t41-,46?/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| | n/a | n/a | 253 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q22N56DJ |
More data for this
Ligand-Target Pair | |
Programmed cell death protein 1
(Homo sapiens) | BDBM482520
(US10919852, Compound TABLE 1.219 | US11708326, Com...)Show SMILES Cc1c(OCCCN2CCC(F)CC2)cccc1-c1cccc2[C@H](CCc12)Oc1cc(OCc2cc(cc(c2)C#N)C#N)c(CN2CCC3(C2)NC(=O)NC3=O)cc1Cl |r| Show InChI InChI=1S/C46H46ClFN6O5/c1-29-35(5-3-8-40(29)57-18-4-14-53-15-11-34(48)12-16-53)36-6-2-7-38-37(36)9-10-41(38)59-43-23-42(58-27-32-20-30(24-49)19-31(21-32)25-50)33(22-39(43)47)26-54-17-13-46(28-54)44(55)51-45(56)52-46/h2-3,5-8,19-23,34,41H,4,9-18,26-28H2,1H3,(H2,51,52,55,56)/t41-,46?/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 253 | n/a | n/a | n/a | n/a | n/a | n/a |
ChemoCentryx, Inc.
US Patent
| Assay Description
96 Well plates were coated with 1 g/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in PBS (W... |
US Patent US10919852 (2021)
BindingDB Entry DOI: 10.7270/Q2RF5Z3R |
More data for this
Ligand-Target Pair | |