Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Metabotropic glutamate receptor 3
(Homo sapiens (Human)) | BDBM290577
(US10099993, Compound 158)Show SMILES Cc1c(OCc2ccc(o2)-c2cccc(c2)C(O)=O)ccc(C(=O)CC(C)(C)C)c1O Show InChI InChI=1S/C25H26O6/c1-15-21(11-9-19(23(15)27)20(26)13-25(2,3)4)30-14-18-8-10-22(31-18)16-6-5-7-17(12-16)24(28)29/h5-12,27H,13-14H2,1-4H3,(H,28,29) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | n/a | n/a | 421 | n/a | n/a | n/a | n/a |
SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE
US Patent
| |
US Patent US10099993 (2018)
BindingDB Entry DOI: 10.7270/Q2Z89FFP |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 2
(Homo sapiens (Human)) | BDBM290577
(US10099993, Compound 158)Show SMILES Cc1c(OCc2ccc(o2)-c2cccc(c2)C(O)=O)ccc(C(=O)CC(C)(C)C)c1O Show InChI InChI=1S/C25H26O6/c1-15-21(11-9-19(23(15)27)20(26)13-25(2,3)4)30-14-18-8-10-22(31-18)16-6-5-7-17(12-16)24(28)29/h5-12,27H,13-14H2,1-4H3,(H,28,29) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | n/a | n/a | 328 | n/a | n/a | 7.3 | 25 |
SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE
US Patent
| Assay Description
Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (... |
US Patent US10099993 (2018)
BindingDB Entry DOI: 10.7270/Q2Z89FFP |
More data for this
Ligand-Target Pair | |