Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 403.8 BDBM50518192

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50518192 (CHEMBL4579581) Show SMILES Cc1c(cnn1-c1ccc(Cl)cc1)C(=O)NCc1ccccc1S(C)(=O)=O Show InChI InChI=1S/C19H18ClN3O3S/c1-13-17(12-22-23(13)16-9-7-15(20)8-10-16)19(24)21-11-14-5-3-4-6-18(14)27(2,25)26/h3-10,12H,11H2,1-2H3,(H,21,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL					Assay Description Antagonist activity at recombinant CCR1 (unknown origin) expressed in non-adherent cells co-expressing Galpha16 assessed as inhibition of MIP-1 alpha...				Bioorg Med Chem Lett 29: 435-440 (2019) Article DOI: 10.1016/j.bmcl.2018.11.015 BindingDB Entry DOI: 10.7270/Q2D79FSV
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