Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 394.7 BDBM50518195Purchase

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50518195 (CHEMBL4462565) Show SMILES Cc1c(nnn1-c1ccc(Cl)cc1)C(=O)NCc1cccc(c1)C(F)(F)F Show InChI InChI=1S/C18H14ClF3N4O/c1-11-16(24-25-26(11)15-7-5-14(19)6-8-15)17(27)23-10-12-3-2-4-13(9-12)18(20,21)22/h2-9H,10H2,1H3,(H,23,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL					Assay Description Antagonist activity at recombinant CCR1 (unknown origin) expressed in non-adherent cells co-expressing Galpha16 assessed as inhibition of MIP-1 alpha...				Bioorg Med Chem Lett 29: 435-440 (2019) Article DOI: 10.1016/j.bmcl.2018.11.015 BindingDB Entry DOI: 10.7270/Q2D79FSV
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