Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Peroxisome proliferator-activated receptor alpha
(Homo sapiens (Human)) | BDBM50450122
(CHEMBL4159849)Show SMILES Cc1cc(C)cc(Oc2ccc3nc(COc4cccc(c4)C(O)=O)n(C)c3n2)c1 Show InChI InChI=1S/C23H21N3O4/c1-14-9-15(2)11-18(10-14)30-21-8-7-19-22(25-21)26(3)20(24-19)13-29-17-6-4-5-16(12-17)23(27)28/h4-12H,13H2,1-3H3,(H,27,28) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co., Ltd.
Curated by ChEMBL
| Assay Description
Agonist activity at recombinant human GAL4-DBD fused PPARalpha LBD expressed in COS7 cells after 24 hrs by luciferase reporter gene assay |
Bioorg Med Chem 26: 5099-5117 (2018)
Article DOI: 10.1016/j.bmc.2018.09.005
BindingDB Entry DOI: 10.7270/Q2XK8J3V |
More data for this
Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50450122
(CHEMBL4159849)Show SMILES Cc1cc(C)cc(Oc2ccc3nc(COc4cccc(c4)C(O)=O)n(C)c3n2)c1 Show InChI InChI=1S/C23H21N3O4/c1-14-9-15(2)11-18(10-14)30-21-8-7-19-22(25-21)26(3)20(24-19)13-29-17-6-4-5-16(12-17)23(27)28/h4-12H,13H2,1-3H3,(H,27,28) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 41 | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co., Ltd.
Curated by ChEMBL
| Assay Description
Agonist activity at recombinant human GAL4-DBD fused PPARgamma LBD expressed in COS7 cells after 24 hrs by luciferase reporter gene assay |
Bioorg Med Chem 26: 5099-5117 (2018)
Article DOI: 10.1016/j.bmc.2018.09.005
BindingDB Entry DOI: 10.7270/Q2XK8J3V |
More data for this
Ligand-Target Pair | |