Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
C-X-C chemokine receptor type 3
(Homo sapiens (Human)) | BDBM249738
(US9447038, 166)Show SMILES Cc1cc(CN(Cc2ccc(F)cc2)C(CC(O)=O)c2ccc(Cl)cc2)ccc1OCCN1C(=O)CCC1=O Show InChI InChI=1S/C30H30ClFN2O5/c1-20-16-22(4-11-27(20)39-15-14-34-28(35)12-13-29(34)36)19-33(18-21-2-9-25(32)10-3-21)26(17-30(37)38)23-5-7-24(31)8-6-23/h2-11,16,26H,12-15,17-19H2,1H3,(H,37,38) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 78 | n/a | n/a | n/a | n/a | n/a | n/a |
Sanofi Co. Ltd
Curated by ChEMBL
| Assay Description
Displacement of [125I]-CXCL10 from human recombinant CXCR3 transfected in Flp-In-CHO cell membranes after 60 mins by gamma counting method |
Bioorg Med Chem Lett 26: 5429-5437 (2016)
Article DOI: 10.1016/j.bmcl.2016.10.038
BindingDB Entry DOI: 10.7270/Q2514164 |
More data for this
Ligand-Target Pair | |
C-X-C motif chemokine 10
(Homo sapiens (Human)) | BDBM249738
(US9447038, 166)Show SMILES Cc1cc(CN(Cc2ccc(F)cc2)C(CC(O)=O)c2ccc(Cl)cc2)ccc1OCCN1C(=O)CCC1=O Show InChI InChI=1S/C30H30ClFN2O5/c1-20-16-22(4-11-27(20)39-15-14-34-28(35)12-13-29(34)36)19-33(18-21-2-9-25(32)10-3-21)26(17-30(37)38)23-5-7-24(31)8-6-23/h2-11,16,26H,12-15,17-19H2,1H3,(H,37,38) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 78 | n/a | n/a | n/a | n/a | n/a | 25 |
Sanofi
US Patent
| Assay Description
The composition of the binding assay buffer is determined in a course of detailed optimization procedure. This resulted in a binding assay buffer con... |
US Patent US9447038 (2016)
BindingDB Entry DOI: 10.7270/Q29G5KQK |
More data for this
Ligand-Target Pair | |