Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 423.4 BDBM50511196

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50511196 (CHEMBL4561177) Show SMILES Cc1cc(CNc2cccc(OC(C)(C)C(O)=O)c2)ccc1OCc1ccc(F)cc1 Show InChI InChI=1S/C25H26FNO4/c1-17-13-19(9-12-23(17)30-16-18-7-10-20(26)11-8-18)15-27-21-5-4-6-22(14-21)31-25(2,3)24(28)29/h4-14,27H,15-16H2,1-3H3,(H,28,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	740	n/a	n/a	n/a	n/a
University of Oklahoma Curated by ChEMBL					Assay Description Agonist activity at human PPARalpha expressed in nonhuman mammalian cells assessed as increase in receptor transcriptional activity incubated for 22 ...				J Med Chem 63: 2854-2876 (2020) Article DOI: 10.1021/acs.jmedchem.9b01189 BindingDB Entry DOI: 10.7270/Q2H998HT
					More data for this Ligand-Target Pair