Found 6 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
DNA damage-inducible transcript 3 protein
(Mus musculus) | BDBM44188
(2-[[4-keto-3-(4-methylbenzyl)quinazolin-2-yl]thio]...)Show SMILES Cc1cc(NC(=O)CSc2nc3ccccc3c(=O)n2Cc2ccc(C)cc2)no1 Show InChI InChI=1S/C22H20N4O3S/c1-14-7-9-16(10-8-14)12-26-21(28)17-5-3-4-6-18(17)23-22(26)30-13-20(27)24-19-11-15(2)29-25-19/h3-11H,12-13H2,1-2H3,(H,24,25,27) | KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
PC cid PC sid UniChem
Similars
| PCBioAssay
| n/a | n/a | 5.41E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Emory University Molecular Libraries Screening Center
Curated by PubChem BioAssay
| Assay Description NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Dr. Randal Kaufman, Univer... |
PubChem Bioassay (2010)
BindingDB Entry DOI: 10.7270/Q2PC30VZ |
More data for this Ligand-Target Pair | |
DNA damage-inducible transcript 3 protein
(Mus musculus) | BDBM44188
(2-[[4-keto-3-(4-methylbenzyl)quinazolin-2-yl]thio]...)Show SMILES Cc1cc(NC(=O)CSc2nc3ccccc3c(=O)n2Cc2ccc(C)cc2)no1 Show InChI InChI=1S/C22H20N4O3S/c1-14-7-9-16(10-8-14)12-26-21(28)17-5-3-4-6-18(17)23-22(26)30-13-20(27)24-19-11-15(2)29-25-19/h3-11H,12-13H2,1-2H3,(H,24,25,27) | KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
PC cid PC sid UniChem
Similars
| PCBioAssay
| n/a | n/a | 5.41E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Emory University Molecular Libraries Screening Center
Curated by PubChem BioAssay
| Assay Description NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Dr. Randal Kaufman, Univer... |
PubChem Bioassay (2011)
BindingDB Entry DOI: 10.7270/Q28C9TQN |
More data for this Ligand-Target Pair | |
X-box-binding protein 1
(Homo sapiens (Human)) | BDBM44188
(2-[[4-keto-3-(4-methylbenzyl)quinazolin-2-yl]thio]...)Show SMILES Cc1cc(NC(=O)CSc2nc3ccccc3c(=O)n2Cc2ccc(C)cc2)no1 Show InChI InChI=1S/C22H20N4O3S/c1-14-7-9-16(10-8-14)12-26-21(28)17-5-3-4-6-18(17)23-22(26)30-13-20(27)24-19-11-15(2)29-25-19/h3-11H,12-13H2,1-2H3,(H,24,25,27) | PDB
KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
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PC cid PC sid UniChem
Similars
| PCBioAssay
| n/a | n/a | 5.53E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Emory University Molecular Libraries Screening Center
Curated by PubChem BioAssay
| Assay Description NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Dr. Randal Kaufman, Univer... |
PubChem Bioassay (2011)
BindingDB Entry DOI: 10.7270/Q2NK3CGB |
More data for this Ligand-Target Pair | |
Solute carrier family 12 member 5
(Homo sapiens (Human)) | BDBM44188
(2-[[4-keto-3-(4-methylbenzyl)quinazolin-2-yl]thio]...)Show SMILES Cc1cc(NC(=O)CSc2nc3ccccc3c(=O)n2Cc2ccc(C)cc2)no1 Show InChI InChI=1S/C22H20N4O3S/c1-14-7-9-16(10-8-14)12-26-21(28)17-5-3-4-6-18(17)23-22(26)30-13-20(27)24-19-11-15(2)29-25-19/h3-11H,12-13H2,1-2H3,(H,24,25,27) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
PC cid PC sid UniChem
Similars
| PCBioAssay
| n/a | n/a | n/a | n/a | 6.51E+4 | n/a | n/a | n/a | n/a |
Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters
Curated by PubChem BioAssay
| Assay Description Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters Assay Provider: Eric Delpire Assay Provider Affliation: Vanderbilt University Gr... |
PubChem Bioassay (2009)
BindingDB Entry DOI: 10.7270/Q2M32T6M |
More data for this Ligand-Target Pair | |
Solute carrier family 12 member 5
(Homo sapiens (Human)) | BDBM44188
(2-[[4-keto-3-(4-methylbenzyl)quinazolin-2-yl]thio]...)Show SMILES Cc1cc(NC(=O)CSc2nc3ccccc3c(=O)n2Cc2ccc(C)cc2)no1 Show InChI InChI=1S/C22H20N4O3S/c1-14-7-9-16(10-8-14)12-26-21(28)17-5-3-4-6-18(17)23-22(26)30-13-20(27)24-19-11-15(2)29-25-19/h3-11H,12-13H2,1-2H3,(H,24,25,27) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
PC cid PC sid UniChem
Similars
| PCBioAssay
| n/a | n/a | n/a | n/a | 8.20E+4 | n/a | n/a | n/a | n/a |
Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters
Curated by PubChem BioAssay
| Assay Description Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters Assay Provider: Eric Delpire Assay Provider Affliation: Vanderbilt University Gr... |
PubChem Bioassay (2009)
BindingDB Entry DOI: 10.7270/Q2Q52N1X |
More data for this Ligand-Target Pair | |
Solute carrier family 12 member 5
(Homo sapiens (Human)) | BDBM44188
(2-[[4-keto-3-(4-methylbenzyl)quinazolin-2-yl]thio]...)Show SMILES Cc1cc(NC(=O)CSc2nc3ccccc3c(=O)n2Cc2ccc(C)cc2)no1 Show InChI InChI=1S/C22H20N4O3S/c1-14-7-9-16(10-8-14)12-26-21(28)17-5-3-4-6-18(17)23-22(26)30-13-20(27)24-19-11-15(2)29-25-19/h3-11H,12-13H2,1-2H3,(H,24,25,27) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
PC cid PC sid UniChem
Similars
| PCBioAssay
| n/a | n/a | n/a | n/a | 1.38E+5 | n/a | n/a | n/a | n/a |
Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters
Curated by PubChem BioAssay
| Assay Description Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters Assay Provider: Eric Delpire Assay Provider Affliation: Vanderbilt University Gr... |
PubChem Bioassay (2009)
BindingDB Entry DOI: 10.7270/Q2PN942B |
More data for this Ligand-Target Pair | |