Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Casein kinase I isoform delta
(Homo sapiens (Human)) | BDBM302744
(2-(7-Chloro-1H- indazol-5- yl)-N5-(4-cyano-3- meth...)Show SMILES Cc1cc(NC(=O)N2CCn3nc(c(C(N)=O)c3C2)-c2cc(Cl)c3[nH]ncc3c2)ccc1[N+]#[C-] |$;;;;HN;;;;;;;;;;;;;;;;;;;;;;;;;;;;;$| Show InChI InChI=1S/C23H19ClN8O2/c1-12-7-15(3-4-17(12)26-2)28-23(34)31-5-6-32-18(11-31)19(22(25)33)21(30-32)13-8-14-10-27-29-20(14)16(24)9-13/h3-4,7-10H,5-6,11H2,1H3,(H2,25,33)(H,27,29)(H,28,34) | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
US Patent
| Assay Description
The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst... |
US Patent US9598423 (2017)
BindingDB Entry DOI: 10.7270/Q2FJ2JT9 |
More data for this
Ligand-Target Pair | |
Casein kinase I isoform epsilon
(Homo sapiens (Human)) | BDBM302744
(2-(7-Chloro-1H- indazol-5- yl)-N5-(4-cyano-3- meth...)Show SMILES Cc1cc(NC(=O)N2CCn3nc(c(C(N)=O)c3C2)-c2cc(Cl)c3[nH]ncc3c2)ccc1[N+]#[C-] |$;;;;HN;;;;;;;;;;;;;;;;;;;;;;;;;;;;;$| Show InChI InChI=1S/C23H19ClN8O2/c1-12-7-15(3-4-17(12)26-2)28-23(34)31-5-6-32-18(11-31)19(22(25)33)21(30-32)13-8-14-10-27-29-20(14)16(24)9-13/h3-4,7-10H,5-6,11H2,1H3,(H2,25,33)(H,27,29)(H,28,34) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
US Patent
| Assay Description
The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst... |
US Patent US9598423 (2017)
BindingDB Entry DOI: 10.7270/Q2FJ2JT9 |
More data for this
Ligand-Target Pair | |