Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 453.5 BDBM50362688

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human))	BDBM50362688 (CHEMBL1939630) Show SMILES Cc1cc(NC(=O)c2ccc3ccccc3c2)ccc1-c1ccc(OCC(C)(C)C(O)=O)cc1 Show InChI InChI=1S/C29H27NO4/c1-19-16-24(30-27(31)23-9-8-20-6-4-5-7-22(20)17-23)12-15-26(19)21-10-13-25(14-11-21)34-18-29(2,3)28(32)33/h4-17H,18H2,1-3H3,(H,30,31)(H,32,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	520	n/a	n/a	n/a	n/a	n/a	n/a
Prosidion Ltd Curated by ChEMBL					Assay Description Inhibition of human recombinant N-terminus FLAG-tagged DGAT1 expressed in baculovirus infected insect Sf9 cells assessed as triglyceride synthesis				Bioorg Med Chem Lett 22: 824-8 (2012) Article DOI: 10.1016/j.bmcl.2011.12.050 BindingDB Entry DOI: 10.7270/Q2R211V4
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