Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 376.4 BDBM395345

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human))	BDBM395345 (US10308636, Example 32-2) Show SMILES Cc1cc(OCC(C)(C)C(O)=O)ncc1-c1ccc(cc1)-c1nc(c[nH]1)C#N Show InChI InChI=1S/C21H20N4O3/c1-13-8-18(28-12-21(2,3)20(26)27)23-11-17(13)14-4-6-15(7-5-14)19-24-10-16(9-22)25-19/h4-8,10-11H,12H2,1-3H3,(H,24,25)(H,26,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description As a buffer used for the enzymatic reaction of DGAT1, 100 mM Tris-HCl (pH7.4), 200 mM Sucrose, and 20 mM MgCl2, 0.125% Bovin Serum Albumin (BSA) were...				Bioorg Med Chem Lett 19: 3485-8 (2009) BindingDB Entry DOI: 10.7270/Q28S4S76
					More data for this Ligand-Target Pair