Found 9 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Peroxisome proliferator-activated receptor delta
(Homo sapiens (Human)) | BDBM50227745
(2-(4-(3-((2-bromo-4-(trifluoromethyl)benzamido)met...)Show SMILES Cc1cc(Oc2cccc(CNC(=O)c3ccc(cc3Br)C(F)(F)F)c2)ccc1OC(C)(C)C(O)=O Show InChI InChI=1S/C26H23BrF3NO5/c1-15-11-19(8-10-22(15)36-25(2,3)24(33)34)35-18-6-4-5-16(12-18)14-31-23(32)20-9-7-17(13-21(20)27)26(28,29)30/h4-13H,14H2,1-3H3,(H,31,32)(H,33,34) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad Nacional Aut£noma de M£xico
Curated by ChEMBL
| Assay Description
Agonist activity at PPARdelta |
Bioorg Med Chem 20: 3523-32 (2012)
Article DOI: 10.1016/j.bmc.2012.04.005
BindingDB Entry DOI: 10.7270/Q2MP54B4 |
More data for this
Ligand-Target Pair | |
Peroxisome proliferator-activated receptor delta
(Homo sapiens (Human)) | BDBM50227745
(2-(4-(3-((2-bromo-4-(trifluoromethyl)benzamido)met...)Show SMILES Cc1cc(Oc2cccc(CNC(=O)c3ccc(cc3Br)C(F)(F)F)c2)ccc1OC(C)(C)C(O)=O Show InChI InChI=1S/C26H23BrF3NO5/c1-15-11-19(8-10-22(15)36-25(2,3)24(33)34)35-18-6-4-5-16(12-18)14-31-23(32)20-9-7-17(13-21(20)27)26(28,29)30/h4-13H,14H2,1-3H3,(H,31,32)(H,33,34) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Eli Lilly and Company
Curated by ChEMBL
| Assay Description
Displacement of [3H]-2-(4-{2-[3-(2,4-difluoro-phenyl)-1-heptyl-ureido]-ethyl}-phenoxy)-2-methyl-butyric acid from human PPARdelta |
Bioorg Med Chem Lett 17: 6744-9 (2008)
Article DOI: 10.1016/j.bmcl.2007.10.047
BindingDB Entry DOI: 10.7270/Q2VT1RTW |
More data for this
Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50227745
(2-(4-(3-((2-bromo-4-(trifluoromethyl)benzamido)met...)Show SMILES Cc1cc(Oc2cccc(CNC(=O)c3ccc(cc3Br)C(F)(F)F)c2)ccc1OC(C)(C)C(O)=O Show InChI InChI=1S/C26H23BrF3NO5/c1-15-11-19(8-10-22(15)36-25(2,3)24(33)34)35-18-6-4-5-16(12-18)14-31-23(32)20-9-7-17(13-21(20)27)26(28,29)30/h4-13H,14H2,1-3H3,(H,31,32)(H,33,34) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 12.0 | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad Nacional Aut£noma de M£xico
Curated by ChEMBL
| Assay Description
Agonist activity at PPARgamma |
Bioorg Med Chem 20: 3523-32 (2012)
Article DOI: 10.1016/j.bmc.2012.04.005
BindingDB Entry DOI: 10.7270/Q2MP54B4 |
More data for this
Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50227745
(2-(4-(3-((2-bromo-4-(trifluoromethyl)benzamido)met...)Show SMILES Cc1cc(Oc2cccc(CNC(=O)c3ccc(cc3Br)C(F)(F)F)c2)ccc1OC(C)(C)C(O)=O Show InChI InChI=1S/C26H23BrF3NO5/c1-15-11-19(8-10-22(15)36-25(2,3)24(33)34)35-18-6-4-5-16(12-18)14-31-23(32)20-9-7-17(13-21(20)27)26(28,29)30/h4-13H,14H2,1-3H3,(H,31,32)(H,33,34) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
Eli Lilly and Company
Curated by ChEMBL
| Assay Description
Displacement of [3H]-2-methyl-2-(4-{3-{propyl-(5-pyridin-2-yl-thiophene-2-sulfonyl)-amino}-propyl}-phenoxy)-propionic acid from human PPARgamma |
Bioorg Med Chem Lett 17: 6744-9 (2008)
Article DOI: 10.1016/j.bmcl.2007.10.047
BindingDB Entry DOI: 10.7270/Q2VT1RTW |
More data for this
Ligand-Target Pair | |
Peroxisome proliferator-activated receptor alpha
(Homo sapiens (Human)) | BDBM50227745
(2-(4-(3-((2-bromo-4-(trifluoromethyl)benzamido)met...)Show SMILES Cc1cc(Oc2cccc(CNC(=O)c3ccc(cc3Br)C(F)(F)F)c2)ccc1OC(C)(C)C(O)=O Show InChI InChI=1S/C26H23BrF3NO5/c1-15-11-19(8-10-22(15)36-25(2,3)24(33)34)35-18-6-4-5-16(12-18)14-31-23(32)20-9-7-17(13-21(20)27)26(28,29)30/h4-13H,14H2,1-3H3,(H,31,32)(H,33,34) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 1.59E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad Nacional Aut£noma de M£xico
Curated by ChEMBL
| Assay Description
Agonist activity at PPARalpha |
Bioorg Med Chem 20: 3523-32 (2012)
Article DOI: 10.1016/j.bmc.2012.04.005
BindingDB Entry DOI: 10.7270/Q2MP54B4 |
More data for this
Ligand-Target Pair | |
Peroxisome proliferator-activated receptor alpha
(Homo sapiens (Human)) | BDBM50227745
(2-(4-(3-((2-bromo-4-(trifluoromethyl)benzamido)met...)Show SMILES Cc1cc(Oc2cccc(CNC(=O)c3ccc(cc3Br)C(F)(F)F)c2)ccc1OC(C)(C)C(O)=O Show InChI InChI=1S/C26H23BrF3NO5/c1-15-11-19(8-10-22(15)36-25(2,3)24(33)34)35-18-6-4-5-16(12-18)14-31-23(32)20-9-7-17(13-21(20)27)26(28,29)30/h4-13H,14H2,1-3H3,(H,31,32)(H,33,34) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 1.59E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Eli Lilly and Company
Curated by ChEMBL
| Assay Description
Displacement of [3H]-2-(4-{2-[3-(2,4-difluoro-phenyl)-1-heptyl-ureido]-ethyl}-phenoxy)-2-methyl-butyric acid from human PPARalpha |
Bioorg Med Chem Lett 17: 6744-9 (2008)
Article DOI: 10.1016/j.bmcl.2007.10.047
BindingDB Entry DOI: 10.7270/Q2VT1RTW |
More data for this
Ligand-Target Pair | |
Peroxisome proliferator-activated receptor alpha
(Homo sapiens (Human)) | BDBM50227745
(2-(4-(3-((2-bromo-4-(trifluoromethyl)benzamido)met...)Show SMILES Cc1cc(Oc2cccc(CNC(=O)c3ccc(cc3Br)C(F)(F)F)c2)ccc1OC(C)(C)C(O)=O Show InChI InChI=1S/C26H23BrF3NO5/c1-15-11-19(8-10-22(15)36-25(2,3)24(33)34)35-18-6-4-5-16(12-18)14-31-23(32)20-9-7-17(13-21(20)27)26(28,29)30/h4-13H,14H2,1-3H3,(H,31,32)(H,33,34) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 590 | n/a | n/a | n/a | n/a |
Eli Lilly and Company
Curated by ChEMBL
| Assay Description
Agonist activity at human PPARalpha expressed in CV1 cells by receptor transactivation assay |
Bioorg Med Chem Lett 17: 6744-9 (2008)
Article DOI: 10.1016/j.bmcl.2007.10.047
BindingDB Entry DOI: 10.7270/Q2VT1RTW |
More data for this
Ligand-Target Pair | |
Peroxisome proliferator-activated receptor delta
(Homo sapiens (Human)) | BDBM50227745
(2-(4-(3-((2-bromo-4-(trifluoromethyl)benzamido)met...)Show SMILES Cc1cc(Oc2cccc(CNC(=O)c3ccc(cc3Br)C(F)(F)F)c2)ccc1OC(C)(C)C(O)=O Show InChI InChI=1S/C26H23BrF3NO5/c1-15-11-19(8-10-22(15)36-25(2,3)24(33)34)35-18-6-4-5-16(12-18)14-31-23(32)20-9-7-17(13-21(20)27)26(28,29)30/h4-13H,14H2,1-3H3,(H,31,32)(H,33,34) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 36 | n/a | n/a | n/a | n/a |
Eli Lilly and Company
Curated by ChEMBL
| Assay Description
Agonist activity at human PPARdelta expressed in CV1 cells by receptor transactivation assay |
Bioorg Med Chem Lett 17: 6744-9 (2008)
Article DOI: 10.1016/j.bmcl.2007.10.047
BindingDB Entry DOI: 10.7270/Q2VT1RTW |
More data for this
Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50227745
(2-(4-(3-((2-bromo-4-(trifluoromethyl)benzamido)met...)Show SMILES Cc1cc(Oc2cccc(CNC(=O)c3ccc(cc3Br)C(F)(F)F)c2)ccc1OC(C)(C)C(O)=O Show InChI InChI=1S/C26H23BrF3NO5/c1-15-11-19(8-10-22(15)36-25(2,3)24(33)34)35-18-6-4-5-16(12-18)14-31-23(32)20-9-7-17(13-21(20)27)26(28,29)30/h4-13H,14H2,1-3H3,(H,31,32)(H,33,34) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 43 | n/a | n/a | n/a | n/a |
Eli Lilly and Company
Curated by ChEMBL
| Assay Description
Agonist activity at human PPARgamma expressed in CV1 cells by receptor transactivation assay |
Bioorg Med Chem Lett 17: 6744-9 (2008)
Article DOI: 10.1016/j.bmcl.2007.10.047
BindingDB Entry DOI: 10.7270/Q2VT1RTW |
More data for this
Ligand-Target Pair | |