Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 456.4 BDBM50467211

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM50467211 (CHEMBL4281179) Show SMILES Cc1cc(Oc2nc(O[C@@H](C(O)=O)C(C)(C)C)c(F)cc2F)cc(c1)-c1cccc(CN)c1 |r| Show InChI InChI=1S/C25H26F2N2O4/c1-14-8-17(16-7-5-6-15(10-16)13-28)11-18(9-14)32-22-19(26)12-20(27)23(29-22)33-21(24(30)31)25(2,3)4/h5-12,21H,13,28H2,1-4H3,(H,30,31)/t21-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	51	n/a	n/a	n/a	n/a	n/a	n/a
Abdulaziz University for Health Sciences Curated by ChEMBL					Assay Description Inhibition of human uPA				Bioorg Med Chem Lett 28: 3372-3375 (2018) Article DOI: 10.1016/j.bmcl.2018.09.001 BindingDB Entry DOI: 10.7270/Q24Q7XNF
					More data for this Ligand-Target Pair
Tissue-type plasminogen activator (Homo sapiens (Human))	BDBM50467211 (CHEMBL4281179) Show SMILES Cc1cc(Oc2nc(O[C@@H](C(O)=O)C(C)(C)C)c(F)cc2F)cc(c1)-c1cccc(CN)c1 |r| Show InChI InChI=1S/C25H26F2N2O4/c1-14-8-17(16-7-5-6-15(10-16)13-28)11-18(9-14)32-22-19(26)12-20(27)23(29-22)33-21(24(30)31)25(2,3)4/h5-12,21H,13,28H2,1-4H3,(H,30,31)/t21-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	470	n/a	n/a	n/a	n/a	n/a	n/a
Abdulaziz University for Health Sciences Curated by ChEMBL					Assay Description Inhibition of human tPA				Bioorg Med Chem Lett 28: 3372-3375 (2018) Article DOI: 10.1016/j.bmcl.2018.09.001 BindingDB Entry DOI: 10.7270/Q24Q7XNF
					More data for this Ligand-Target Pair
Plasminogen (Homo sapiens (Human))	BDBM50467211 (CHEMBL4281179) Show SMILES Cc1cc(Oc2nc(O[C@@H](C(O)=O)C(C)(C)C)c(F)cc2F)cc(c1)-c1cccc(CN)c1 |r| Show InChI InChI=1S/C25H26F2N2O4/c1-14-8-17(16-7-5-6-15(10-16)13-28)11-18(9-14)32-22-19(26)12-20(27)23(29-22)33-21(24(30)31)25(2,3)4/h5-12,21H,13,28H2,1-4H3,(H,30,31)/t21-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Abdulaziz University for Health Sciences Curated by ChEMBL					Assay Description Inhibition of human plasmin				Bioorg Med Chem Lett 28: 3372-3375 (2018) Article DOI: 10.1016/j.bmcl.2018.09.001 BindingDB Entry DOI: 10.7270/Q24Q7XNF
					More data for this Ligand-Target Pair