Found 3 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50463273
(CHEMBL4237675)Show SMILES Cc1cc(SC(Cc2c(F)cccc2C(F)(F)F)c2ccc(cc2)-c2ccc(F)cc2)ccc1OCC(O)=O Show InChI InChI=1S/C30H23F5O3S/c1-18-15-23(13-14-27(18)38-17-29(36)37)39-28(16-24-25(30(33,34)35)3-2-4-26(24)32)21-7-5-19(6-8-21)20-9-11-22(31)12-10-20/h2-15,28H,16-17H2,1H3,(H,36,37) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Daegu-Gyeongbuk Medical Innovation Foundation
Curated by ChEMBL
| Assay Description
Transactivation of human PPARgamma expressed in monkey CV-1 cells coexpressing TK-PPRE-Luc after 24 hrs by luciferase reporter gene assay |
Bioorg Med Chem 26: 4382-4389 (2018)
Article DOI: 10.1016/j.bmc.2018.06.044
BindingDB Entry DOI: 10.7270/Q2DJ5J8Z |
More data for this
Ligand-Target Pair | |
Peroxisome proliferator-activated receptor alpha
(Homo sapiens (Human)) | BDBM50463273
(CHEMBL4237675)Show SMILES Cc1cc(SC(Cc2c(F)cccc2C(F)(F)F)c2ccc(cc2)-c2ccc(F)cc2)ccc1OCC(O)=O Show InChI InChI=1S/C30H23F5O3S/c1-18-15-23(13-14-27(18)38-17-29(36)37)39-28(16-24-25(30(33,34)35)3-2-4-26(24)32)21-7-5-19(6-8-21)20-9-11-22(31)12-10-20/h2-15,28H,16-17H2,1H3,(H,36,37) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Daegu-Gyeongbuk Medical Innovation Foundation
Curated by ChEMBL
| Assay Description
Transactivation of human PPARalpha expressed in monkey CV-1 cells coexpressing TK-PPRE-Luc after 24 hrs by luciferase reporter gene assay |
Bioorg Med Chem 26: 4382-4389 (2018)
Article DOI: 10.1016/j.bmc.2018.06.044
BindingDB Entry DOI: 10.7270/Q2DJ5J8Z |
More data for this
Ligand-Target Pair | |
Peroxisome proliferator-activated receptor delta
(Homo sapiens (Human)) | BDBM50463273
(CHEMBL4237675)Show SMILES Cc1cc(SC(Cc2c(F)cccc2C(F)(F)F)c2ccc(cc2)-c2ccc(F)cc2)ccc1OCC(O)=O Show InChI InChI=1S/C30H23F5O3S/c1-18-15-23(13-14-27(18)38-17-29(36)37)39-28(16-24-25(30(33,34)35)3-2-4-26(24)32)21-7-5-19(6-8-21)20-9-11-22(31)12-10-20/h2-15,28H,16-17H2,1H3,(H,36,37) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 38 | n/a | n/a | n/a | n/a |
Daegu-Gyeongbuk Medical Innovation Foundation
Curated by ChEMBL
| Assay Description
Transactivation of human PPARdelta expressed in monkey CV-1 cells coexpressing TK-PPRE-Luc after 24 hrs by luciferase reporter gene assay |
Bioorg Med Chem 26: 4382-4389 (2018)
Article DOI: 10.1016/j.bmc.2018.06.044
BindingDB Entry DOI: 10.7270/Q2DJ5J8Z |
More data for this
Ligand-Target Pair | |