Found 3 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Peroxisome proliferator-activated receptor delta
(Homo sapiens (Human)) | BDBM50463276
(CHEMBL4240310)Show SMILES Cc1cc(SC(Cc2cc(F)c(F)c(F)c2)c2ccc(cc2)-c2ccc(F)cc2)ccc1OCC(O)=O Show InChI InChI=1S/C29H22F4O3S/c1-17-12-23(10-11-26(17)36-16-28(34)35)37-27(15-18-13-24(31)29(33)25(32)14-18)21-4-2-19(3-5-21)20-6-8-22(30)9-7-20/h2-14,27H,15-16H2,1H3,(H,34,35) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 65 | n/a | n/a | n/a | n/a |
Daegu-Gyeongbuk Medical Innovation Foundation
Curated by ChEMBL
| Assay Description
Transactivation of human PPARdelta expressed in monkey CV-1 cells coexpressing TK-PPRE-Luc after 24 hrs by luciferase reporter gene assay |
Bioorg Med Chem 26: 4382-4389 (2018)
Article DOI: 10.1016/j.bmc.2018.06.044
BindingDB Entry DOI: 10.7270/Q2DJ5J8Z |
More data for this
Ligand-Target Pair | |
Peroxisome proliferator-activated receptor alpha
(Homo sapiens (Human)) | BDBM50463276
(CHEMBL4240310)Show SMILES Cc1cc(SC(Cc2cc(F)c(F)c(F)c2)c2ccc(cc2)-c2ccc(F)cc2)ccc1OCC(O)=O Show InChI InChI=1S/C29H22F4O3S/c1-17-12-23(10-11-26(17)36-16-28(34)35)37-27(15-18-13-24(31)29(33)25(32)14-18)21-4-2-19(3-5-21)20-6-8-22(30)9-7-20/h2-14,27H,15-16H2,1H3,(H,34,35) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Daegu-Gyeongbuk Medical Innovation Foundation
Curated by ChEMBL
| Assay Description
Transactivation of human PPARalpha expressed in monkey CV-1 cells coexpressing TK-PPRE-Luc after 24 hrs by luciferase reporter gene assay |
Bioorg Med Chem 26: 4382-4389 (2018)
Article DOI: 10.1016/j.bmc.2018.06.044
BindingDB Entry DOI: 10.7270/Q2DJ5J8Z |
More data for this
Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50463276
(CHEMBL4240310)Show SMILES Cc1cc(SC(Cc2cc(F)c(F)c(F)c2)c2ccc(cc2)-c2ccc(F)cc2)ccc1OCC(O)=O Show InChI InChI=1S/C29H22F4O3S/c1-17-12-23(10-11-26(17)36-16-28(34)35)37-27(15-18-13-24(31)29(33)25(32)14-18)21-4-2-19(3-5-21)20-6-8-22(30)9-7-20/h2-14,27H,15-16H2,1H3,(H,34,35) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Daegu-Gyeongbuk Medical Innovation Foundation
Curated by ChEMBL
| Assay Description
Transactivation of human PPARgamma expressed in monkey CV-1 cells coexpressing TK-PPRE-Luc after 24 hrs by luciferase reporter gene assay |
Bioorg Med Chem 26: 4382-4389 (2018)
Article DOI: 10.1016/j.bmc.2018.06.044
BindingDB Entry DOI: 10.7270/Q2DJ5J8Z |
More data for this
Ligand-Target Pair | |