Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 462.0 BDBM50361789

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysosomal Pro-X carboxypeptidase (Homo sapiens (Human))	BDBM50361789 (CHEMBL1938525) Show SMILES Cc1cc(cc(C)n1)C(NC(=O)CCN1CCC(CC1)c1ccccc1)c1ccc(Cl)cc1 Show InChI InChI=1S/C28H32ClN3O/c1-20-18-25(19-21(2)30-20)28(24-8-10-26(29)11-9-24)31-27(33)14-17-32-15-12-23(13-16-32)22-6-4-3-5-7-22/h3-11,18-19,23,28H,12-17H2,1-2H3,(H,31,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	79	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of recombinant human PrCP using Mca-Ala-Pro-Lys(Dnp)-OH as substrate measured for 30 mins by continuous fluorometric assay				Bioorg Med Chem Lett 22: 658-65 (2011) Article DOI: 10.1016/j.bmcl.2011.10.060 BindingDB Entry DOI: 10.7270/Q2B56K50
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