Found 8 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Coagulation factor XI
(Homo sapiens (Human)) | BDBM32854
((1,3-dioxoisoindol-2-yl) 2,5-dimethylbenzenesulfon...)Show SMILES Cc1ccc(C)c(c1)S(=O)(=O)ON1C(=O)c2ccccc2C1=O Show InChI InChI=1S/C16H13NO5S/c1-10-7-8-11(2)14(9-10)23(20,21)22-17-15(18)12-5-3-4-6-13(12)16(17)19/h3-9H,1-2H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
PC cid PC sid UniChem
Similars
| PCBioAssay
| n/a | n/a | 762 | n/a | n/a | n/a | n/a | 7.4 | 23 |
PCMD
Curated by PubChem BioAssay
| Assay Description Factor XIa (0.23 ug/mL) was incubated with Boc-Glu-Ala-Arg-AMC substrate (15 uM) in 10 uL of assay buffer for 2 hr at room temperature. Read fluoresc... |
PubChem Bioassay (2008)
BindingDB Entry DOI: 10.7270/Q2H993J6 |
More data for this Ligand-Target Pair | |
DNA damage-inducible transcript 3 protein
(Mus musculus) | BDBM32854
((1,3-dioxoisoindol-2-yl) 2,5-dimethylbenzenesulfon...)Show SMILES Cc1ccc(C)c(c1)S(=O)(=O)ON1C(=O)c2ccccc2C1=O Show InChI InChI=1S/C16H13NO5S/c1-10-7-8-11(2)14(9-10)23(20,21)22-17-15(18)12-5-3-4-6-13(12)16(17)19/h3-9H,1-2H3 | KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
PC cid PC sid UniChem
Similars
| PCBioAssay
| n/a | n/a | 1.45E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Emory University Molecular Libraries Screening Center
Curated by PubChem BioAssay
| Assay Description NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Dr. Randal Kaufman, Univer... |
PubChem Bioassay (2010)
BindingDB Entry DOI: 10.7270/Q2PC30VZ |
More data for this Ligand-Target Pair | |
DNA damage-inducible transcript 3 protein
(Mus musculus) | BDBM32854
((1,3-dioxoisoindol-2-yl) 2,5-dimethylbenzenesulfon...)Show SMILES Cc1ccc(C)c(c1)S(=O)(=O)ON1C(=O)c2ccccc2C1=O Show InChI InChI=1S/C16H13NO5S/c1-10-7-8-11(2)14(9-10)23(20,21)22-17-15(18)12-5-3-4-6-13(12)16(17)19/h3-9H,1-2H3 | KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
PC cid PC sid UniChem
Similars
| PCBioAssay
| n/a | n/a | 1.45E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Emory University Molecular Libraries Screening Center
Curated by PubChem BioAssay
| Assay Description NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Dr. Randal Kaufman, Univer... |
PubChem Bioassay (2011)
BindingDB Entry DOI: 10.7270/Q28C9TQN |
More data for this Ligand-Target Pair | |
Prothrombin
(Homo sapiens (Human)) | BDBM32854
((1,3-dioxoisoindol-2-yl) 2,5-dimethylbenzenesulfon...)Show SMILES Cc1ccc(C)c(c1)S(=O)(=O)ON1C(=O)c2ccccc2C1=O Show InChI InChI=1S/C16H13NO5S/c1-10-7-8-11(2)14(9-10)23(20,21)22-17-15(18)12-5-3-4-6-13(12)16(17)19/h3-9H,1-2H3 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| Purchase
PC cid PC sid UniChem
Similars
| PCBioAssay
| n/a | n/a | 1.57E+3 | n/a | n/a | n/a | n/a | 7.5 | 23 |
PCMD
Curated by PubChem BioAssay
| Assay Description HTS was performed using 217,350 compounds of the MLSCN library individually plated into 10ul 1536 compound plates at a concentration of 2.5 mM each, ... |
PubChem Bioassay (2008)
BindingDB Entry DOI: 10.7270/Q2K64GDN |
More data for this Ligand-Target Pair | |
Coagulation factor XII
(Homo sapiens (Human)) | BDBM32854
((1,3-dioxoisoindol-2-yl) 2,5-dimethylbenzenesulfon...)Show SMILES Cc1ccc(C)c(c1)S(=O)(=O)ON1C(=O)c2ccccc2C1=O Show InChI InChI=1S/C16H13NO5S/c1-10-7-8-11(2)14(9-10)23(20,21)22-17-15(18)12-5-3-4-6-13(12)16(17)19/h3-9H,1-2H3 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| Purchase
PC cid PC sid UniChem
Similars
| PCBioAssay
| n/a | n/a | 2.59E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
PCMD
Curated by PubChem BioAssay
| Assay Description Molecular Library Screening Center Network (MLSCN) Penn Center for Molecular Discovery (PCMD) Assay Provider: Scott L. Diamond, University of Pennsy... |
PubChem Bioassay (2008)
BindingDB Entry DOI: 10.7270/Q21G0JQS |
More data for this Ligand-Target Pair | |
X-box-binding protein 1
(Homo sapiens (Human)) | BDBM32854
((1,3-dioxoisoindol-2-yl) 2,5-dimethylbenzenesulfon...)Show SMILES Cc1ccc(C)c(c1)S(=O)(=O)ON1C(=O)c2ccccc2C1=O Show InChI InChI=1S/C16H13NO5S/c1-10-7-8-11(2)14(9-10)23(20,21)22-17-15(18)12-5-3-4-6-13(12)16(17)19/h3-9H,1-2H3 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| Purchase
PC cid PC sid UniChem
Similars
| PCBioAssay
| n/a | n/a | 2.88E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Emory University Molecular Libraries Screening Center
Curated by PubChem BioAssay
| Assay Description NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Dr. Randal Kaufman, Univer... |
PubChem Bioassay (2011)
BindingDB Entry DOI: 10.7270/Q2NK3CGB |
More data for this Ligand-Target Pair | |
Endothelial PAS domain-containing protein 1
(Homo sapiens (Human)) | BDBM32854
((1,3-dioxoisoindol-2-yl) 2,5-dimethylbenzenesulfon...)Show SMILES Cc1ccc(C)c(c1)S(=O)(=O)ON1C(=O)c2ccccc2C1=O Show InChI InChI=1S/C16H13NO5S/c1-10-7-8-11(2)14(9-10)23(20,21)22-17-15(18)12-5-3-4-6-13(12)16(17)19/h3-9H,1-2H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| Purchase
PC cid PC sid UniChem
Similars
| PCBioAssay
| n/a | n/a | 8.46E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Burnham Center for Chemical Genomics
Curated by PubChem BioAssay
| |
PubChem Bioassay (2012)
BindingDB Entry DOI: 10.7270/Q2WS8RVZ |
More data for this Ligand-Target Pair | |
Mitochondrial import inner membrane translocase subunit TIM10
(Saccharomyces cerevisiae S288c) | BDBM32854
((1,3-dioxoisoindol-2-yl) 2,5-dimethylbenzenesulfon...)Show SMILES Cc1ccc(C)c(c1)S(=O)(=O)ON1C(=O)c2ccccc2C1=O Show InChI InChI=1S/C16H13NO5S/c1-10-7-8-11(2)14(9-10)23(20,21)22-17-15(18)12-5-3-4-6-13(12)16(17)19/h3-9H,1-2H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| Purchase
PC cid PC sid UniChem
Similars
| PCBioAssay
| n/a | n/a | 2.21E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Burnham Center for Chemical Genomics
Curated by PubChem BioAssay
| Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute(SBMRI, San Diego, CA... |
PubChem Bioassay (2010)
BindingDB Entry DOI: 10.7270/Q2F18X6W |
More data for this Ligand-Target Pair | |