Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 348.3 BDBM50390587

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Probable G-protein coupled receptor 142 (Homo sapiens (Human))	BDBM50390587 (CHEMBL2069492) Show SMILES Cc1ccc(C[C@H](N)C(=O)Nc2cc(c[nH]c2=O)-c2ccncc2)cc1 |r| Show InChI InChI=1S/C20H20N4O2/c1-13-2-4-14(5-3-13)10-17(21)19(25)24-18-11-16(12-23-20(18)26)15-6-8-22-9-7-15/h2-9,11-12,17H,10,21H2,1H3,(H,23,26)(H,24,25)/t17-/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	6.60E+3	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Agonist activity at human GPR142 expressed in HEK293 cells assessed as inositol phosphate accumulation using [3H]-inositol after 1 hr by scintillatio...				Bioorg Med Chem Lett 22: 5942-7 (2012) Article DOI: 10.1016/j.bmcl.2012.07.063 BindingDB Entry DOI: 10.7270/Q2VH5PXT
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