Found 2 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Bifunctional epoxide hydrolase 2
(Homo sapiens (Human)) | BDBM50511336
(CHEMBL4575840)Show InChI InChI=1S/C23H23NO2/c1-18-7-9-19(10-8-18)15-16-24-23(25)17-20-11-13-22(14-12-20)26-21-5-3-2-4-6-21/h2-14H,15-17H2,1H3,(H,24,25) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Goethe University Frankfurt
Curated by ChEMBL
| Assay Description Inhibition of full length human soluble epoxide hydrolase (1 to 555 residues) expressed in Escherichia coli BL21(DE3) using non-fluorescent PHOME as ... |
ACS Med Chem Lett 11: 298-302 (2020)
Article DOI: 10.1021/acsmedchemlett.9b00330 BindingDB Entry DOI: 10.7270/Q2M3303Q |
More data for this Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50511336
(CHEMBL4575840)Show InChI InChI=1S/C23H23NO2/c1-18-7-9-19(10-8-18)15-16-24-23(25)17-20-11-13-22(14-12-20)26-21-5-3-2-4-6-21/h2-14H,15-17H2,1H3,(H,24,25) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Goethe University Frankfurt
Curated by ChEMBL
| Assay Description Inhibition of (His)6 tagged human recombinant LTA4H expressed in Escherichia coli BL21(DE3) using non-fluorescent L-arginine-7-amino-4-methylcoumarin... |
ACS Med Chem Lett 11: 298-302 (2020)
Article DOI: 10.1021/acsmedchemlett.9b00330 BindingDB Entry DOI: 10.7270/Q2M3303Q |
More data for this Ligand-Target Pair | |