Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 349.3 BDBM50342911

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 6 hits in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dual specificity protein kinase CLK4 (Homo sapiens (Human))	BDBM50342911 (5-(4-((5-methylfuran-2-yl)methylamino)quinazolin-6...) Show SMILES Cc1ccc(CNc2ncnc3ccc(cc23)-c2ccc(o2)C(O)=O)o1 Show InChI InChI=1S/C19H15N3O4/c1-11-2-4-13(25-11)9-20-18-14-8-12(3-5-15(14)21-10-22-18)16-6-7-17(26-16)19(23)24/h2-8,10H,9H2,1H3,(H,23,24)(H,20,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	104	n/a	n/a	n/a	n/a	n/a	n/a
National Human Genome Research Institute Curated by ChEMBL					Assay Description Inhibition of Clk4 kinase using ATP as substrate by 33P radiolabelled kinase assay				Bioorg Med Chem Lett 21: 3152-8 (2011) Article DOI: 10.1016/j.bmcl.2011.02.114 BindingDB Entry DOI: 10.7270/Q2J67H83
					More data for this Ligand-Target Pair
Dual specificity protein kinase CLK2 (Homo sapiens (Human))	BDBM50342911 (5-(4-((5-methylfuran-2-yl)methylamino)quinazolin-6...) Show SMILES Cc1ccc(CNc2ncnc3ccc(cc23)-c2ccc(o2)C(O)=O)o1 Show InChI InChI=1S/C19H15N3O4/c1-11-2-4-13(25-11)9-20-18-14-8-12(3-5-15(14)21-10-22-18)16-6-7-17(26-16)19(23)24/h2-8,10H,9H2,1H3,(H,23,24)(H,20,21,22)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.36E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Human Genome Research Institute Curated by ChEMBL					Assay Description Inhibition of Clk2 kinase using ATP as substrate by 33P radiolabelled kinase assay				Bioorg Med Chem Lett 21: 3152-8 (2011) Article DOI: 10.1016/j.bmcl.2011.02.114 BindingDB Entry DOI: 10.7270/Q2J67H83
					More data for this Ligand-Target Pair
Dual specificity protein kinase CLK1 (Homo sapiens (Human))	BDBM50342911 (5-(4-((5-methylfuran-2-yl)methylamino)quinazolin-6...) Show SMILES Cc1ccc(CNc2ncnc3ccc(cc23)-c2ccc(o2)C(O)=O)o1 Show InChI InChI=1S/C19H15N3O4/c1-11-2-4-13(25-11)9-20-18-14-8-12(3-5-15(14)21-10-22-18)16-6-7-17(26-16)19(23)24/h2-8,10H,9H2,1H3,(H,23,24)(H,20,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.56E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Human Genome Research Institute Curated by ChEMBL					Assay Description Inhibition of Clk1 kinase using ATP as substrate by 33P radiolabelled kinase assay				Bioorg Med Chem Lett 21: 3152-8 (2011) Article DOI: 10.1016/j.bmcl.2011.02.114 BindingDB Entry DOI: 10.7270/Q2J67H83
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1B (Homo sapiens (Human))	BDBM50342911 (5-(4-((5-methylfuran-2-yl)methylamino)quinazolin-6...) Show SMILES Cc1ccc(CNc2ncnc3ccc(cc23)-c2ccc(o2)C(O)=O)o1 Show InChI InChI=1S/C19H15N3O4/c1-11-2-4-13(25-11)9-20-18-14-8-12(3-5-15(14)21-10-22-18)16-6-7-17(26-16)19(23)24/h2-8,10H,9H2,1H3,(H,23,24)(H,20,21,22)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.93E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Human Genome Research Institute Curated by ChEMBL					Assay Description Inhibition of Dyrk1B kinase using ATP as substrate by 33P radiolabelled kinase assay				Bioorg Med Chem Lett 21: 3152-8 (2011) Article DOI: 10.1016/j.bmcl.2011.02.114 BindingDB Entry DOI: 10.7270/Q2J67H83
					More data for this Ligand-Target Pair
Dual specificity protein kinase CLK3 (Homo sapiens (Human))	BDBM50342911 (5-(4-((5-methylfuran-2-yl)methylamino)quinazolin-6...) Show SMILES Cc1ccc(CNc2ncnc3ccc(cc23)-c2ccc(o2)C(O)=O)o1 Show InChI InChI=1S/C19H15N3O4/c1-11-2-4-13(25-11)9-20-18-14-8-12(3-5-15(14)21-10-22-18)16-6-7-17(26-16)19(23)24/h2-8,10H,9H2,1H3,(H,23,24)(H,20,21,22)	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
National Human Genome Research Institute Curated by ChEMBL					Assay Description Inhibition of Clk3 kinase using ATP as substrate by 33P radiolabelled kinase assay				Bioorg Med Chem Lett 21: 3152-8 (2011) Article DOI: 10.1016/j.bmcl.2011.02.114 BindingDB Entry DOI: 10.7270/Q2J67H83
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human))	BDBM50342911 (5-(4-((5-methylfuran-2-yl)methylamino)quinazolin-6...) Show SMILES Cc1ccc(CNc2ncnc3ccc(cc23)-c2ccc(o2)C(O)=O)o1 Show InChI InChI=1S/C19H15N3O4/c1-11-2-4-13(25-11)9-20-18-14-8-12(3-5-15(14)21-10-22-18)16-6-7-17(26-16)19(23)24/h2-8,10H,9H2,1H3,(H,23,24)(H,20,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
National Human Genome Research Institute Curated by ChEMBL					Assay Description Inhibition of Dyrk1A kinase using ATP as substrate by 33P radiolabelled kinase assay				Bioorg Med Chem Lett 21: 3152-8 (2011) Article DOI: 10.1016/j.bmcl.2011.02.114 BindingDB Entry DOI: 10.7270/Q2J67H83
					More data for this Ligand-Target Pair