Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 437.4 BDBM372655

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM372655 (N-[2-(3-Cyano-4-methyl-benzyl)-2H-[1,2,3]triazol-4...) Show SMILES Cc1ccc(Cn2ncc(NC(=O)Cc3ccc(OC4CC(F)(F)C4)cc3)n2)cc1C#N Show InChI InChI=1S/C23H21F2N5O2/c1-15-2-3-17(8-18(15)12-26)14-30-27-13-21(29-30)28-22(31)9-16-4-6-19(7-5-16)32-20-10-23(24,25)11-20/h2-8,13,20H,9-11,14H2,1H3,(H,28,29,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta					Assay Description Stock solutions of test compounds are prepared to a concentration of 10 mM in DMSO. For the Cav3.2 assay, serial dilutions of the compounds are prepa...				J Med Chem 49: 1668-83 (2006) BindingDB Entry DOI: 10.7270/Q2794709
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