Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 405.4 BDBM372647

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM372647 (N-[2-(3-Cyano-4-methyl-benzyl)-2H-[1,2,3]triazol-4...) Show SMILES Cc1ccc(Cn2ncc(NC(=O)Cc3ccc(cc3)C3(F)COC3)n2)cc1C#N Show InChI InChI=1S/C22H20FN5O2/c1-15-2-3-17(8-18(15)10-24)12-28-25-11-20(27-28)26-21(29)9-16-4-6-19(7-5-16)22(23)13-30-14-22/h2-8,11H,9,12-14H2,1H3,(H,26,27,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	310	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta					Assay Description Stock solutions of test compounds are prepared to a concentration of 10 mM in DMSO. For the Cav3.2 assay, serial dilutions of the compounds are prepa...				J Med Chem 49: 1668-83 (2006) BindingDB Entry DOI: 10.7270/Q2794709
					More data for this Ligand-Target Pair