Found 3 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Bromodomain-containing protein 4
(Homo sapiens (Human)) | BDBM50504157
(CHEMBL4520352)Show SMILES Cc1ccc(NC(=O)CN2C(=O)NC(Cc3ccccc3)C2=O)cc1S(=O)(=O)N1CCCCC1 Show InChI InChI=1S/C24H28N4O5S/c1-17-10-11-19(15-21(17)34(32,33)27-12-6-3-7-13-27)25-22(29)16-28-23(30)20(26-24(28)31)14-18-8-4-2-5-9-18/h2,4-5,8-11,15,20H,3,6-7,12-14,16H2,1H3,(H,25,29)(H,26,31) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet 
| Purchase
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | <5.01E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Cellzome
Curated by ChEMBL
| Assay Description
Displacement of Alexa Fluor 647 labelled ligand from His6-tagged BRD4 BD2 (1 to 477 residues)/BD1 Y97A mutant (unknown origin) after 30 mins by TR-FR... |
J Med Chem 62: 7506-7525 (2019)
Article DOI: 10.1021/acs.jmedchem.9b00673
BindingDB Entry DOI: 10.7270/Q22R3VZV |
More data for this
Ligand-Target Pair | |
Bromodomain-containing protein 4
(Homo sapiens (Human)) | BDBM50504157
(CHEMBL4520352)Show SMILES Cc1ccc(NC(=O)CN2C(=O)NC(Cc3ccccc3)C2=O)cc1S(=O)(=O)N1CCCCC1 Show InChI InChI=1S/C24H28N4O5S/c1-17-10-11-19(15-21(17)34(32,33)27-12-6-3-7-13-27)25-22(29)16-28-23(30)20(26-24(28)31)14-18-8-4-2-5-9-18/h2,4-5,8-11,15,20H,3,6-7,12-14,16H2,1H3,(H,25,29)(H,26,31) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| Purchase
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | <5.01E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Cellzome
Curated by ChEMBL
| Assay Description
Displacement of Alexa Fluor 647 labelled ligand from His6-tagged BRD4 BD1 (1 to 477 residues)/BD2 Y390A mutant (unknown origin) after 30 mins by TR-F... |
J Med Chem 62: 7506-7525 (2019)
Article DOI: 10.1021/acs.jmedchem.9b00673
BindingDB Entry DOI: 10.7270/Q22R3VZV |
More data for this
Ligand-Target Pair | |
ATPase family AAA domain-containing protein 2
(Homo sapiens (Human)) | BDBM50504157
(CHEMBL4520352)Show SMILES Cc1ccc(NC(=O)CN2C(=O)NC(Cc3ccccc3)C2=O)cc1S(=O)(=O)N1CCCCC1 Show InChI InChI=1S/C24H28N4O5S/c1-17-10-11-19(15-21(17)34(32,33)27-12-6-3-7-13-27)25-22(29)16-28-23(30)20(26-24(28)31)14-18-8-4-2-5-9-18/h2,4-5,8-11,15,20H,3,6-7,12-14,16H2,1H3,(H,25,29)(H,26,31) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| Purchase
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | <1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Cellzome
Curated by ChEMBL
| Assay Description
Displacement of SGRG-K(Ac)-GG-K(Ac)-GLG-K(Ac)-GGAKRHRKV-biotin) from His6/FLAG-tagged TEV fused ATAD2 bromodomain (981 to 1121 residues) (unknown ori... |
J Med Chem 62: 7506-7525 (2019)
Article DOI: 10.1021/acs.jmedchem.9b00673
BindingDB Entry DOI: 10.7270/Q22R3VZV |
More data for this
Ligand-Target Pair | |