Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Beta-1 adrenergic receptor
(Homo sapiens (Human)) | BDBM50027873
(CHEMBL2348214)Show SMILES Cc1ccc(NC(=O)NCCNCC(O)COc2ccc(OCCOC3CCCC3)cc2)cc1 Show InChI InChI=1S/C26H37N3O5/c1-20-6-8-21(9-7-20)29-26(31)28-15-14-27-18-22(30)19-34-25-12-10-24(11-13-25)33-17-16-32-23-4-2-3-5-23/h6-13,22-23,27,30H,2-5,14-19H2,1H3,(H2,28,29,31) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a |
University of Nottingham
Curated by ChEMBL
| Assay Description
Displacement of [3H]-CGP12177 from human beta1 adrenoceptor expressed in CHOK1 cells after 2 hrs by scintillation counting analysis |
J Med Chem 56: 3852-65 (2013)
Article DOI: 10.1021/jm400348g
BindingDB Entry DOI: 10.7270/Q2445NV6 |
More data for this
Ligand-Target Pair | |
Beta-2 adrenergic receptor
(Homo sapiens (Human)) | BDBM50027873
(CHEMBL2348214)Show SMILES Cc1ccc(NC(=O)NCCNCC(O)COc2ccc(OCCOC3CCCC3)cc2)cc1 Show InChI InChI=1S/C26H37N3O5/c1-20-6-8-21(9-7-20)29-26(31)28-15-14-27-18-22(30)19-34-25-12-10-24(11-13-25)33-17-16-32-23-4-2-3-5-23/h6-13,22-23,27,30H,2-5,14-19H2,1H3,(H2,28,29,31) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | 1.59E+3 | n/a | n/a | n/a | n/a | n/a |
University of Nottingham
Curated by ChEMBL
| Assay Description
Displacement of [3H]-CGP12177 from human beta2 adrenoceptor expressed in CHOK1 cells after 2 hrs by scintillation counting analysis |
J Med Chem 56: 3852-65 (2013)
Article DOI: 10.1021/jm400348g
BindingDB Entry DOI: 10.7270/Q2445NV6 |
More data for this
Ligand-Target Pair | |