Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Prostaglandin E synthase
(Homo sapiens (Human)) | BDBM197611
(US9216968, 211 | US9732066, 211)Show SMILES Cc1ccc(NC(=O)c2cc(NC(=O)c3cc(Cl)ccc3Cl)cc3[nH]c(nc23)C2(C)CC2)cc1Cl Show InChI InChI=1S/C26H21Cl3N4O2/c1-13-3-5-15(11-20(13)29)30-24(35)18-10-16(31-23(34)17-9-14(27)4-6-19(17)28)12-21-22(18)33-25(32-21)26(2)7-8-26/h3-6,9-12H,7-8H2,1-2H3,(H,30,35)(H,31,34)(H,32,33) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 2.5 | n/a | n/a | n/a | n/a | n/a | n/a |
NIPPON SHINY AKU CO., LTD.
US Patent
| Assay Description
mPGES-1 microsome fractions were prepared from CHO-K1 cells transiently transfected with plasmid encoding the human mPGES-1cDNA. Microsomes were dilu... |
US Patent US9732066 (2017)
BindingDB Entry DOI: 10.7270/Q2K35WSW |
More data for this
Ligand-Target Pair | |
Prostaglandin E synthase
(Homo sapiens (Human)) | BDBM197611
(US9216968, 211 | US9732066, 211)Show SMILES Cc1ccc(NC(=O)c2cc(NC(=O)c3cc(Cl)ccc3Cl)cc3[nH]c(nc23)C2(C)CC2)cc1Cl Show InChI InChI=1S/C26H21Cl3N4O2/c1-13-3-5-15(11-20(13)29)30-24(35)18-10-16(31-23(34)17-9-14(27)4-6-19(17)28)12-21-22(18)33-25(32-21)26(2)7-8-26/h3-6,9-12H,7-8H2,1-2H3,(H,30,35)(H,31,34)(H,32,33) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 2.5 | n/a | n/a | n/a | n/a | n/a | n/a |
NIPPON SHINYAKU CO., LTD.
US Patent
| Assay Description
mPGES-1 microsome fractions were prepared from CHO-K1 cells transiently transfected with plasmid encoding the human mPGES-1cDNA. Microsomes were dilu... |
US Patent US9216968 (2015)
BindingDB Entry DOI: 10.7270/Q2KS6QCQ |
More data for this
Ligand-Target Pair | |