Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Beta-1 adrenergic receptor
(Homo sapiens (Human)) | BDBM50273114
(4-((7S)-7-{[(2R)-2-Hydroxy-2-(4-methylphenyl)ethyl...)Show SMILES Cc1ccc(cc1)[C@@H](O)CN[C@H]1CCc2ccc(cc2C1)-c1ccc(cc1)C(O)=O |r| Show InChI InChI=1S/C26H27NO3/c1-17-2-4-20(5-3-17)25(28)16-27-24-13-12-19-8-11-22(14-23(19)15-24)18-6-9-21(10-7-18)26(29)30/h2-11,14,24-25,27-28H,12-13,15-16H2,1H3,(H,29,30)/t24-,25-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a |
Astellas Pharma Inc
Curated by ChEMBL
| Assay Description
Agonist activity at human cloned beta-1 adrenergic receptor expressed in CHO cells assessed as cAMP accumulation |
J Med Chem 51: 4804-22 (2008)
Article DOI: 10.1021/jm800222k
BindingDB Entry DOI: 10.7270/Q25D8SQ8 |
More data for this
Ligand-Target Pair | |
Beta-3 adrenergic receptor
(Homo sapiens (Human)) | BDBM50273114
(4-((7S)-7-{[(2R)-2-Hydroxy-2-(4-methylphenyl)ethyl...)Show SMILES Cc1ccc(cc1)[C@@H](O)CN[C@H]1CCc2ccc(cc2C1)-c1ccc(cc1)C(O)=O |r| Show InChI InChI=1S/C26H27NO3/c1-17-2-4-20(5-3-17)25(28)16-27-24-13-12-19-8-11-22(14-23(19)15-24)18-6-9-21(10-7-18)26(29)30/h2-11,14,24-25,27-28H,12-13,15-16H2,1H3,(H,29,30)/t24-,25-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.790 | n/a | n/a | n/a | n/a |
Astellas Pharma Inc
Curated by ChEMBL
| Assay Description
Agonist activity at human cloned beta3 adrenergic receptor expressed in CHO cells assessed as cAMP accumulation |
J Med Chem 51: 4804-22 (2008)
Article DOI: 10.1021/jm800222k
BindingDB Entry DOI: 10.7270/Q25D8SQ8 |
More data for this
Ligand-Target Pair | |