Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 367.4 BDBM50129961

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prothrombin (Homo sapiens (Human))	BDBM50129961 (4-(4-Methyl-7-p-tolyl-quinolin-2-yloxy)-benzamidin...) Show SMILES Cc1ccc(cc1)-c1ccc2c(C)cc(Oc3ccc(cc3)C(N)=N)nc2c1 Show InChI InChI=1S/C24H21N3O/c1-15-3-5-17(6-4-15)19-9-12-21-16(2)13-23(27-22(21)14-19)28-20-10-7-18(8-11-20)24(25)26/h3-14H,1-2H3,(H3,25,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharma KG Curated by ChEMBL					Assay Description In vitro inhibitory activity against thrombin in human plasma				Bioorg Med Chem Lett 13: 2291-5 (2003) BindingDB Entry DOI: 10.7270/Q2QJ7GP2
					More data for this Ligand-Target Pair
Serine protease 1 (Homo sapiens (Human))	BDBM50129961 (4-(4-Methyl-7-p-tolyl-quinolin-2-yloxy)-benzamidin...) Show SMILES Cc1ccc(cc1)-c1ccc2c(C)cc(Oc3ccc(cc3)C(N)=N)nc2c1 Show InChI InChI=1S/C24H21N3O/c1-15-3-5-17(6-4-15)19-9-12-21-16(2)13-23(27-22(21)14-19)28-20-10-7-18(8-11-20)24(25)26/h3-14H,1-2H3,(H3,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharma KG Curated by ChEMBL					Assay Description Inhibitory activity of the compound against trypsin				Bioorg Med Chem Lett 13: 2291-5 (2003) BindingDB Entry DOI: 10.7270/Q2QJ7GP2
					More data for this Ligand-Target Pair
Plasminogen (Homo sapiens (Human))	BDBM50129961 (4-(4-Methyl-7-p-tolyl-quinolin-2-yloxy)-benzamidin...) Show SMILES Cc1ccc(cc1)-c1ccc2c(C)cc(Oc3ccc(cc3)C(N)=N)nc2c1 Show InChI InChI=1S/C24H21N3O/c1-15-3-5-17(6-4-15)19-9-12-21-16(2)13-23(27-22(21)14-19)28-20-10-7-18(8-11-20)24(25)26/h3-14H,1-2H3,(H3,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.22E+4	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharma KG Curated by ChEMBL					Assay Description Inhibitory activity of the compound against plasmin in human plasma				Bioorg Med Chem Lett 13: 2291-5 (2003) BindingDB Entry DOI: 10.7270/Q2QJ7GP2
					More data for this Ligand-Target Pair