Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 462.4 BDBM201283

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM201283 (US9187424, 47) Show SMILES Cc1ccc(cc1)C1=C(C#N)C(=O)NC(C1)(c1ccc(OCc2ccccc2)cc1)C(F)(F)F |c:8| Show InChI InChI=1S/C27H21F3N2O2/c1-18-7-9-20(10-8-18)23-15-26(27(28,29)30,32-25(33)24(23)16-31)21-11-13-22(14-12-21)34-17-19-5-3-2-4-6-19/h2-14H,15,17H2,1H3,(H,32,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	756	n/a	n/a	n/a	n/a	7.4	25
Bristol-Myers Squibb Company US Patent					Assay Description MGAT2 enzyme was assayed using membranes isolated from Sf9 cells expressing the recombinant human MGAT2 cDNA with 2-monooleoylglycerol and [3H]-oleoy...				US Patent US9187424 (2015) BindingDB Entry DOI: 10.7270/Q2FQ9VFG
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