Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 382.4 BDBM150290

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor IX (Homo sapiens (Human))	BDBM150290 (US8987242, 2) Show SMILES Cc1ccc(cc1)N1CCOC(C(O)C(=O)Nc2ccc(cc2)C(N)=N)C1=O Show InChI InChI=1S/C20H22N4O4/c1-12-2-8-15(9-3-12)24-10-11-28-17(20(24)27)16(25)19(26)23-14-6-4-13(5-7-14)18(21)22/h2-9,16-17,25H,10-11H2,1H3,(H3,21,22)(H,23,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	30	n/a	n/a	n/a	n/a	8.0	25
Merck Sharp & Dohme Corp.; Mochida Pharmaceuticals Co., Ltd. US Patent					Assay Description Inhibitory activity against factor IXa was tested using the substrate SPECTROFLUOR FIXa (american diagnostica inc.; 500 West Avenue, Stamford, Conn. ...				US Patent US8987242 (2015) BindingDB Entry DOI: 10.7270/Q2ZW1JNS
					More data for this Ligand-Target Pair