Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50155527
(CHEMBL3775422)Show SMILES Cc1ccc(cc1)S(=O)(=O)N1CC2(C[C@H]1C(=O)N\N=C\c1ccccc1[N+]([O-])=O)SCCS2 |r| Show InChI InChI=1S/C21H22N4O5S3/c1-15-6-8-17(9-7-15)33(29,30)24-14-21(31-10-11-32-21)12-19(24)20(26)23-22-13-16-4-2-3-5-18(16)25(27)28/h2-9,13,19H,10-12,14H2,1H3,(H,23,26)/b22-13+/t19-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 240 | n/a | n/a | n/a | n/a | n/a | n/a |
Shandong University
Curated by ChEMBL
| Assay Description
Inhibition of gelatinase A (unknown origin) after 30 mins using succinylated gelatin as substrate |
Bioorg Med Chem 24: 2125-36 (2016)
Article DOI: 10.1016/j.bmc.2016.03.043
BindingDB Entry DOI: 10.7270/Q28S4RSZ |
More data for this
Ligand-Target Pair | |
Aminopeptidase N
(Sus scrofa (Pig)) | BDBM50155527
(CHEMBL3775422)Show SMILES Cc1ccc(cc1)S(=O)(=O)N1CC2(C[C@H]1C(=O)N\N=C\c1ccccc1[N+]([O-])=O)SCCS2 |r| Show InChI InChI=1S/C21H22N4O5S3/c1-15-6-8-17(9-7-15)33(29,30)24-14-21(31-10-11-32-21)12-19(24)20(26)23-22-13-16-4-2-3-5-18(16)25(27)28/h2-9,13,19H,10-12,14H2,1H3,(H,23,26)/b22-13+/t19-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Shandong University
Curated by ChEMBL
| Assay Description
Inhibition of porcine microsomal aminopeptidase N preincubated for 30 mins using L-Leu-p-nitroanilide as substrate by UV-VIS spectrophotometer |
Bioorg Med Chem 24: 2125-36 (2016)
Article DOI: 10.1016/j.bmc.2016.03.043
BindingDB Entry DOI: 10.7270/Q28S4RSZ |
More data for this
Ligand-Target Pair | |