Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 470.9 BDBM405824

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor IX (Homo sapiens (Human))	BDBM405824 (US10351558, Example 4) Show SMILES Cc1ccc2c3CC(C)(CCc3nn2c1)NC(=O)c1ccc(cc1Cl)-n1cnc2ncccc12 Show InChI InChI=1S/C26H23ClN6O/c1-16-5-8-22-19-13-26(2,10-9-21(19)31-33(22)14-16)30-25(34)18-7-6-17(12-20(18)27)32-15-29-24-23(32)4-3-11-28-24/h3-8,11-12,14-15H,9-10,13H2,1-2H3,(H,30,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	13.7	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp US Patent					Assay Description TBD				US Patent US10351558 (2019) BindingDB Entry DOI: 10.7270/Q2SX6GKR
					More data for this Ligand-Target Pair