Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 518.9 BDBM405911

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor IX (Homo sapiens (Human))	BDBM405911 (US10351558, Example 86) Show SMILES Cc1ccc2n3CC(CCc3nc2c1)(NC(=O)c1ccc(cc1Cl)-n1cnnc1)c1cc(F)cc(F)c1 Show InChI InChI=1S/C27H21ClF2N6O/c1-16-2-5-24-23(8-16)33-25-6-7-27(13-36(24)25,17-9-18(29)11-19(30)10-17)34-26(37)21-4-3-20(12-22(21)28)35-14-31-32-15-35/h2-5,8-12,14-15H,6-7,13H2,1H3,(H,34,37)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7.21	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp US Patent					Assay Description TBD				US Patent US10351558 (2019) BindingDB Entry DOI: 10.7270/Q2SX6GKR
					More data for this Ligand-Target Pair