Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 277.3 BDBM50062520

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 3 (Homo sapiens (Human))	BDBM50062520 ((1S,2S)-2-((R)-1-Amino-1-carboxy-3-m-tolyl-propyl)...) Show SMILES Cc1cccc(CC[C@@](N)([C@H]2C[C@@H]2C(O)=O)C(O)=O)c1 Show InChI InChI=1S/C15H19NO4/c1-9-3-2-4-10(7-9)5-6-15(16,14(19)20)12-8-11(12)13(17)18/h2-4,7,11-12H,5-6,8,16H2,1H3,(H,17,18)(H,19,20)/t11-,12-,15+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Effect on 1S,3R-ACPD-induced inhibition of forskolin stimulated cyclic-AMP in RGT cells expressing human Metabotropic glutamate receptor 3				J Med Chem 41: 358-78 (1998) Article DOI: 10.1021/jm970498o BindingDB Entry DOI: 10.7270/Q2XP7423
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50062520 ((1S,2S)-2-((R)-1-Amino-1-carboxy-3-m-tolyl-propyl)...) Show SMILES Cc1cccc(CC[C@@](N)([C@H]2C[C@@H]2C(O)=O)C(O)=O)c1 Show InChI InChI=1S/C15H19NO4/c1-9-3-2-4-10(7-9)5-6-15(16,14(19)20)12-8-11(12)13(17)18/h2-4,7,11-12H,5-6,8,16H2,1H3,(H,17,18)(H,19,20)/t11-,12-,15+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Effect on 1S,3R-ACPD-induced inhibition of forskolin stimulated cyclic-AMP in RGT cells expressing human Metabotropic glutamate receptor 2				J Med Chem 41: 358-78 (1998) Article DOI: 10.1021/jm970498o BindingDB Entry DOI: 10.7270/Q2XP7423
					More data for this Ligand-Target Pair