Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 380.8 BDBM50341091Purchase

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuromedin-K receptor (Homo sapiens (Human))	BDBM50341091 ((3-(4-chlorophenyl)-1H-pyrazol-5-yl)(4-o-tolylpipe...) Show SMILES Cc1ccccc1N1CCN(CC1)C(=O)c1cc(n[nH]1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C21H21ClN4O/c1-15-4-2-3-5-20(15)25-10-12-26(13-11-25)21(27)19-14-18(23-24-19)16-6-8-17(22)9-7-16/h2-9,14H,10-13H2,1H3,(H,23,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Euroscreen SA Curated by ChEMBL					Assay Description Antagonist activity at human recombinant NK3 receptor expressed in CHO cells assessed as inhibition of NKB-induced increase of intracellular calcium ...				Bioorg Med Chem Lett 21: 1991-6 (2011) Article DOI: 10.1016/j.bmcl.2011.02.033 BindingDB Entry DOI: 10.7270/Q2B56K16
					More data for this Ligand-Target Pair