Found 8 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Branched-chain-amino-acid aminotransferase, cytosolic
(Homo sapiens (Human)) | BDBM50607315
(BAY-069)Show SMILES Cc1ccccc1Oc1cc(-n2c(=O)cc([nH]c2=O)C(F)(F)F)c2ccccc2c1Cl |(20.53,-12.27,;19.26,-11.42,;19.36,-9.88,;18.08,-9.03,;16.7,-9.71,;16.59,-11.25,;17.87,-12.1,;17.76,-13.64,;16.38,-14.32,;15.11,-13.47,;13.73,-14.15,;12.45,-13.3,;12.56,-11.76,;13.94,-11.08,;11.28,-10.9,;9.9,-11.59,;9.79,-13.13,;11.07,-13.98,;10.96,-15.52,;8.45,-11.09,;8.55,-9.56,;7.17,-10.24,;7.29,-12.11,;13.62,-15.7,;12.24,-16.38,;12.13,-17.91,;13.41,-18.77,;14.79,-18.09,;14.9,-16.55,;16.28,-15.87,;17.55,-16.72,)| | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| Purchase
MCE
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 31 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c00441
BindingDB Entry DOI: 10.7270/Q2SN0F31 |
More data for this
Ligand-Target Pair | |
Branched-chain-amino-acid aminotransferase, mitochondrial
(Homo sapiens (Human)) | BDBM50607315
(BAY-069)Show SMILES Cc1ccccc1Oc1cc(-n2c(=O)cc([nH]c2=O)C(F)(F)F)c2ccccc2c1Cl |(20.53,-12.27,;19.26,-11.42,;19.36,-9.88,;18.08,-9.03,;16.7,-9.71,;16.59,-11.25,;17.87,-12.1,;17.76,-13.64,;16.38,-14.32,;15.11,-13.47,;13.73,-14.15,;12.45,-13.3,;12.56,-11.76,;13.94,-11.08,;11.28,-10.9,;9.9,-11.59,;9.79,-13.13,;11.07,-13.98,;10.96,-15.52,;8.45,-11.09,;8.55,-9.56,;7.17,-10.24,;7.29,-12.11,;13.62,-15.7,;12.24,-16.38,;12.13,-17.91,;13.41,-18.77,;14.79,-18.09,;14.9,-16.55,;16.28,-15.87,;17.55,-16.72,)| | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| Purchase
MCE
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 153 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c00441
BindingDB Entry DOI: 10.7270/Q2SN0F31 |
More data for this
Ligand-Target Pair | |
Branched-chain-amino-acid aminotransferase, cytosolic
(Homo sapiens (Human)) | BDBM50607315
(BAY-069)Show SMILES Cc1ccccc1Oc1cc(-n2c(=O)cc([nH]c2=O)C(F)(F)F)c2ccccc2c1Cl |(20.53,-12.27,;19.26,-11.42,;19.36,-9.88,;18.08,-9.03,;16.7,-9.71,;16.59,-11.25,;17.87,-12.1,;17.76,-13.64,;16.38,-14.32,;15.11,-13.47,;13.73,-14.15,;12.45,-13.3,;12.56,-11.76,;13.94,-11.08,;11.28,-10.9,;9.9,-11.59,;9.79,-13.13,;11.07,-13.98,;10.96,-15.52,;8.45,-11.09,;8.55,-9.56,;7.17,-10.24,;7.29,-12.11,;13.62,-15.7,;12.24,-16.38,;12.13,-17.91,;13.41,-18.77,;14.79,-18.09,;14.9,-16.55,;16.28,-15.87,;17.55,-16.72,)| | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
MCE
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 186 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c00441
BindingDB Entry DOI: 10.7270/Q2SN0F31 |
More data for this
Ligand-Target Pair | |
Branched-chain-amino-acid aminotransferase, cytosolic
(Homo sapiens (Human)) | BDBM50607315
(BAY-069)Show SMILES Cc1ccccc1Oc1cc(-n2c(=O)cc([nH]c2=O)C(F)(F)F)c2ccccc2c1Cl |(20.53,-12.27,;19.26,-11.42,;19.36,-9.88,;18.08,-9.03,;16.7,-9.71,;16.59,-11.25,;17.87,-12.1,;17.76,-13.64,;16.38,-14.32,;15.11,-13.47,;13.73,-14.15,;12.45,-13.3,;12.56,-11.76,;13.94,-11.08,;11.28,-10.9,;9.9,-11.59,;9.79,-13.13,;11.07,-13.98,;10.96,-15.52,;8.45,-11.09,;8.55,-9.56,;7.17,-10.24,;7.29,-12.11,;13.62,-15.7,;12.24,-16.38,;12.13,-17.91,;13.41,-18.77,;14.79,-18.09,;14.9,-16.55,;16.28,-15.87,;17.55,-16.72,)| | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
MCE
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 186 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c00441
BindingDB Entry DOI: 10.7270/Q2SN0F31 |
More data for this
Ligand-Target Pair | |
Branched-chain-amino-acid aminotransferase, mitochondrial
(Homo sapiens (Human)) | BDBM50607315
(BAY-069)Show SMILES Cc1ccccc1Oc1cc(-n2c(=O)cc([nH]c2=O)C(F)(F)F)c2ccccc2c1Cl |(20.53,-12.27,;19.26,-11.42,;19.36,-9.88,;18.08,-9.03,;16.7,-9.71,;16.59,-11.25,;17.87,-12.1,;17.76,-13.64,;16.38,-14.32,;15.11,-13.47,;13.73,-14.15,;12.45,-13.3,;12.56,-11.76,;13.94,-11.08,;11.28,-10.9,;9.9,-11.59,;9.79,-13.13,;11.07,-13.98,;10.96,-15.52,;8.45,-11.09,;8.55,-9.56,;7.17,-10.24,;7.29,-12.11,;13.62,-15.7,;12.24,-16.38,;12.13,-17.91,;13.41,-18.77,;14.79,-18.09,;14.9,-16.55,;16.28,-15.87,;17.55,-16.72,)| | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| Purchase
MCE
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.16E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c00441
BindingDB Entry DOI: 10.7270/Q2SN0F31 |
More data for this
Ligand-Target Pair | |
Branched-chain-amino-acid aminotransferase, mitochondrial
(Homo sapiens (Human)) | BDBM50607315
(BAY-069)Show SMILES Cc1ccccc1Oc1cc(-n2c(=O)cc([nH]c2=O)C(F)(F)F)c2ccccc2c1Cl |(20.53,-12.27,;19.26,-11.42,;19.36,-9.88,;18.08,-9.03,;16.7,-9.71,;16.59,-11.25,;17.87,-12.1,;17.76,-13.64,;16.38,-14.32,;15.11,-13.47,;13.73,-14.15,;12.45,-13.3,;12.56,-11.76,;13.94,-11.08,;11.28,-10.9,;9.9,-11.59,;9.79,-13.13,;11.07,-13.98,;10.96,-15.52,;8.45,-11.09,;8.55,-9.56,;7.17,-10.24,;7.29,-12.11,;13.62,-15.7,;12.24,-16.38,;12.13,-17.91,;13.41,-18.77,;14.79,-18.09,;14.9,-16.55,;16.28,-15.87,;17.55,-16.72,)| | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| Purchase
MCE
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.16E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c00441
BindingDB Entry DOI: 10.7270/Q2SN0F31 |
More data for this
Ligand-Target Pair | |
Aspartate aminotransferase, cytoplasmic
(Homo sapiens) | BDBM50607315
(BAY-069)Show SMILES Cc1ccccc1Oc1cc(-n2c(=O)cc([nH]c2=O)C(F)(F)F)c2ccccc2c1Cl |(20.53,-12.27,;19.26,-11.42,;19.36,-9.88,;18.08,-9.03,;16.7,-9.71,;16.59,-11.25,;17.87,-12.1,;17.76,-13.64,;16.38,-14.32,;15.11,-13.47,;13.73,-14.15,;12.45,-13.3,;12.56,-11.76,;13.94,-11.08,;11.28,-10.9,;9.9,-11.59,;9.79,-13.13,;11.07,-13.98,;10.96,-15.52,;8.45,-11.09,;8.55,-9.56,;7.17,-10.24,;7.29,-12.11,;13.62,-15.7,;12.24,-16.38,;12.13,-17.91,;13.41,-18.77,;14.79,-18.09,;14.9,-16.55,;16.28,-15.87,;17.55,-16.72,)| | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| Purchase
MCE
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c00441
BindingDB Entry DOI: 10.7270/Q2SN0F31 |
More data for this
Ligand-Target Pair | |
Aspartate aminotransferase, mitochondrial
(Homo sapiens) | BDBM50607315
(BAY-069)Show SMILES Cc1ccccc1Oc1cc(-n2c(=O)cc([nH]c2=O)C(F)(F)F)c2ccccc2c1Cl |(20.53,-12.27,;19.26,-11.42,;19.36,-9.88,;18.08,-9.03,;16.7,-9.71,;16.59,-11.25,;17.87,-12.1,;17.76,-13.64,;16.38,-14.32,;15.11,-13.47,;13.73,-14.15,;12.45,-13.3,;12.56,-11.76,;13.94,-11.08,;11.28,-10.9,;9.9,-11.59,;9.79,-13.13,;11.07,-13.98,;10.96,-15.52,;8.45,-11.09,;8.55,-9.56,;7.17,-10.24,;7.29,-12.11,;13.62,-15.7,;12.24,-16.38,;12.13,-17.91,;13.41,-18.77,;14.79,-18.09,;14.9,-16.55,;16.28,-15.87,;17.55,-16.72,)| | PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
AffyNet
| Purchase
MCE
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c00441
BindingDB Entry DOI: 10.7270/Q2SN0F31 |
More data for this
Ligand-Target Pair | |