Found 2 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Receptor tyrosine-protein kinase erbB-2
(Homo sapiens (Human)) | BDBM50204143
(5-methyl-N-(1-(pyridin-3-ylmethyl)-1H-indazol-5-yl...)Show InChI InChI=1S/C20H17N7/c1-14-6-8-26-19(14)20(22-13-24-26)25-17-4-5-18-16(9-17)11-23-27(18)12-15-3-2-7-21-10-15/h2-11,13H,12H2,1H3,(H,22,24,25) | PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 250 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description Inhibition of human recombinant cytoplasmic HER2 kinase expressed in Sf9 cells |
Bioorg Med Chem Lett 17: 2036-42 (2007)
Article DOI: 10.1016/j.bmcl.2007.01.002 BindingDB Entry DOI: 10.7270/Q2GT5MVS |
More data for this Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50204143
(5-methyl-N-(1-(pyridin-3-ylmethyl)-1H-indazol-5-yl...)Show InChI InChI=1S/C20H17N7/c1-14-6-8-26-19(14)20(22-13-24-26)25-17-4-5-18-16(9-17)11-23-27(18)12-15-3-2-7-21-10-15/h2-11,13H,12H2,1H3,(H,22,24,25) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description Inhibition of EGFR |
Bioorg Med Chem Lett 17: 2036-42 (2007)
Article DOI: 10.1016/j.bmcl.2007.01.002 BindingDB Entry DOI: 10.7270/Q2GT5MVS |
More data for this Ligand-Target Pair | |