Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 374.4 BDBM365230

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase kinase kinase 12 (Homo sapiens (Human))	BDBM365230 ((4-Methyl-pyridin-2-yl)- [2-methyl-6-(1-pyridin- 2...) Show SMILES Cc1ccnc(Nc2cc(nc(C)n2)C2CCCN(Cc3ccccn3)C2)c1 Show InChI InChI=1S/C22H26N6/c1-16-8-10-24-21(12-16)27-22-13-20(25-17(2)26-22)18-6-5-11-28(14-18)15-19-7-3-4-9-23-19/h3-4,7-10,12-13,18H,5-6,11,14-15H2,1-2H3,(H,24,25,26,27)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	293	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description DLK kinase reactions (20 μL) containing 5 nM N-terminally GST-tagged DLK (catalytic domain amino acid 1-520) (Carna Bioscience), 40 nM N-termina...				J Med Chem 50: 3515-27 (2007) BindingDB Entry DOI: 10.7270/Q2J38VWN
					More data for this Ligand-Target Pair