Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50159576
(CHEMBL3785252)Show SMILES Cc1ccoc1C(=O)Nc1ccc(N2CCc3ccccc3C2=O)c(Cl)c1 Show InChI InChI=1S/C21H17ClN2O3/c1-13-9-11-27-19(13)20(25)23-15-6-7-18(17(22)12-15)24-10-8-14-4-2-3-5-16(14)21(24)26/h2-7,9,11-12H,8,10H2,1H3,(H,23,25) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 776 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulatory activity at human mGlu1 receptor expressed in wild type T-Rex293 cells assessed as increase in glutamate-induced calci... |
Bioorg Med Chem Lett 26: 1869-72 (2016)
Article DOI: 10.1016/j.bmcl.2016.03.031
BindingDB Entry DOI: 10.7270/Q2Z03B11 |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50159576
(CHEMBL3785252)Show SMILES Cc1ccoc1C(=O)Nc1ccc(N2CCc3ccccc3C2=O)c(Cl)c1 Show InChI InChI=1S/C21H17ClN2O3/c1-13-9-11-27-19(13)20(25)23-15-6-7-18(17(22)12-15)24-10-8-14-4-2-3-5-16(14)21(24)26/h2-7,9,11-12H,8,10H2,1H3,(H,23,25) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 781 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulatory activity at human mGlu1 receptor expressed in wild type T-Rex293 cells assessed as increase in glutamate-induced calci... |
Bioorg Med Chem Lett 26: 1869-72 (2016)
Article DOI: 10.1016/j.bmcl.2016.03.031
BindingDB Entry DOI: 10.7270/Q2Z03B11 |
More data for this
Ligand-Target Pair | |