Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 449.5 BDBM50604034

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 10 hits in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50604034 (CHEMBL5187885 | US20230312529, Compound 6d) Show SMILES Cc1cnc(Nc2ccc(cc2)N2CCS(=O)(=O)CC2)nc1Nc1ccc2cn[nH]c2c1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	39	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50604034 (CHEMBL5187885 | US20230312529, Compound 6d) Show SMILES Cc1cnc(Nc2ccc(cc2)N2CCS(=O)(=O)CC2)nc1Nc1ccc2cn[nH]c2c1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01732 BindingDB Entry DOI: 10.7270/Q2QR527K
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha (Homo sapiens (Human))	BDBM50604034 (CHEMBL5187885 | US20230312529, Compound 6d) Show SMILES Cc1cnc(Nc2ccc(cc2)N2CCS(=O)(=O)CC2)nc1Nc1ccc2cn[nH]c2c1 Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	42	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01732 BindingDB Entry DOI: 10.7270/Q2QR527K
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha (Homo sapiens (Human))	BDBM50604034 (CHEMBL5187885 | US20230312529, Compound 6d) Show SMILES Cc1cnc(Nc2ccc(cc2)N2CCS(=O)(=O)CC2)nc1Nc1ccc2cn[nH]c2c1 Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	46	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha (Homo sapiens (Human))	BDBM50604034 (CHEMBL5187885 | US20230312529, Compound 6d) Show SMILES Cc1cnc(Nc2ccc(cc2)N2CCS(=O)(=O)CC2)nc1Nc1ccc2cn[nH]c2c1 Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	66.6	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50604034 (CHEMBL5187885 | US20230312529, Compound 6d) Show SMILES Cc1cnc(Nc2ccc(cc2)N2CCS(=O)(=O)CC2)nc1Nc1ccc2cn[nH]c2c1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	70.3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM50604034 (CHEMBL5187885 | US20230312529, Compound 6d) Show SMILES Cc1cnc(Nc2ccc(cc2)N2CCS(=O)(=O)CC2)nc1Nc1ccc2cn[nH]c2c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	99	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 2 (Homo sapiens (Human))	BDBM50604034 (CHEMBL5187885 | US20230312529, Compound 6d) Show SMILES Cc1cnc(Nc2ccc(cc2)N2CCS(=O)(=O)CC2)nc1Nc1ccc2cn[nH]c2c1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	117	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
ALK tyrosine kinase receptor (Homo sapiens (Human))	BDBM50604034 (CHEMBL5187885 | US20230312529, Compound 6d) Show SMILES Cc1cnc(Nc2ccc(cc2)N2CCS(=O)(=O)CC2)nc1Nc1ccc2cn[nH]c2c1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	186	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Inhibitor of nuclear factor kappa-B kinase subunit beta (Homo sapiens (Human))	BDBM50604034 (CHEMBL5187885 | US20230312529, Compound 6d) Show SMILES Cc1cnc(Nc2ccc(cc2)N2CCS(=O)(=O)CC2)nc1Nc1ccc2cn[nH]c2c1 Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	619	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair