Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 443.5 BDBM50301200

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuropeptide Y receptor type 1 (Homo sapiens (Human))	BDBM50301200 (6-((4,5-dimethyloxazol-2-ylthio)methyl)-N-((6-(flu...) Show SMILES Cc1nc(SCc2cc(cc(NCc3cccc(CF)n3)n2)N2CCOCC2)oc1C Show InChI InChI=1S/C22H26FN5O2S/c1-15-16(2)30-22(25-15)31-14-19-10-20(28-6-8-29-9-7-28)11-21(27-19)24-13-18-5-3-4-17(12-23)26-18/h3-5,10-11H,6-9,12-14H2,1-2H3,(H,24,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]-PYY from human NPYY1 receptor overexpressed in CHO cell membrane after 120 mins by scintillation counting				Bioorg Med Chem Lett 19: 5124-7 (2009) Article DOI: 10.1016/j.bmcl.2009.07.030 BindingDB Entry DOI: 10.7270/Q26M36WZ
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