Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 504.8 BDBM487830

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM487830 (1-(benzo[d]thiazol-4-yl)-N-(5- chloro-2-methyl-6-(...) Show SMILES Cc1nc(c(Cl)cc1NC(=O)c1cnn(c1C(F)(F)F)-c1cccc2scnc12)-n1nccn1 Show InChI InChI=1S/C20H12ClF3N8OS/c1-10-13(7-12(21)18(29-10)32-26-5-6-27-32)30-19(33)11-8-28-31(17(11)20(22,23)24)14-3-2-4-15-16(14)25-9-34-15/h2-9H,1H3,(H,30,33)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	282	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description MALT1 protease activity was assessed in an in vitro assay using a tetrapeptide as substrate and full-length MALT1 protein (Strep-MALT1(1-824)-His) pu...				US Patent US10954214 (2021) BindingDB Entry DOI: 10.7270/Q2SX6HB1
					More data for this Ligand-Target Pair