Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 415.8 BDBM176371

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human))	BDBM176371 (US9688696, 87) Show SMILES Cc1nc(no1)-c1ccc(cc1)N1CCN(CC1)C(=O)Nc1c(F)cccc1Cl Show InChI InChI=1S/C20H19ClFN5O2/c1-13-23-19(25-29-13)14-5-7-15(8-6-14)26-9-11-27(12-10-26)20(28)24-18-16(21)3-2-4-17(18)22/h2-8H,9-12H2,1H3,(H,24,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.31E+3	n/a	n/a	n/a	n/a	7.4	25
Janssen Pharmaceutica N.V. US Patent					Assay Description DGAT activity in membrane preparations was assayed in 50 mM Tris-HCl (pH 7.4), 150 mM MgCl2, 1 mM EDTA and 0.2% BSA, containing 50 μM DAG, 32 &#...				US Patent US9688696 (2017) BindingDB Entry DOI: 10.7270/Q24X55ZP
					More data for this Ligand-Target Pair