Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 444.9 BDBM28712

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM28712 (2-[4-({[2-(4-chlorophenyl)-4-methyl-1,3-thiazol-5-...) Show SMILES Cc1nc(sc1C(=O)NCc1ccc(OC(C)(C)C(O)=O)cc1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C22H21ClN2O4S/c1-13-18(30-20(25-13)15-6-8-16(23)9-7-15)19(26)24-12-14-4-10-17(11-5-14)29-22(2,3)21(27)28/h4-11H,12H2,1-3H3,(H,24,26)(H,27,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	10	n/a	n/a	n/a	n/a
GSK					Assay Description The ligand binding domain for PPAR was fused to the yeast transcription factor GAL4 DNA binding domain. CV-1 cells were transiently transfected with ...				J Med Chem 50: 685-95 (2007) Article DOI: 10.1021/jm058056x BindingDB Entry DOI: 10.7270/Q2RN3669
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM28712 (2-[4-({[2-(4-chlorophenyl)-4-methyl-1,3-thiazol-5-...) Show SMILES Cc1nc(sc1C(=O)NCc1ccc(OC(C)(C)C(O)=O)cc1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C22H21ClN2O4S/c1-13-18(30-20(25-13)15-6-8-16(23)9-7-15)19(26)24-12-14-4-10-17(11-5-14)29-22(2,3)21(27)28/h4-11H,12H2,1-3H3,(H,24,26)(H,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
GSK					Assay Description The ligand binding domain for PPAR was fused to the yeast transcription factor GAL4 DNA binding domain. CV-1 cells were transiently transfected with ...				J Med Chem 50: 685-95 (2007) Article DOI: 10.1021/jm058056x BindingDB Entry DOI: 10.7270/Q2RN3669
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM28712 (2-[4-({[2-(4-chlorophenyl)-4-methyl-1,3-thiazol-5-...) Show SMILES Cc1nc(sc1C(=O)NCc1ccc(OC(C)(C)C(O)=O)cc1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C22H21ClN2O4S/c1-13-18(30-20(25-13)15-6-8-16(23)9-7-15)19(26)24-12-14-4-10-17(11-5-14)29-22(2,3)21(27)28/h4-11H,12H2,1-3H3,(H,24,26)(H,27,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	5.40E+3	n/a	n/a	n/a	n/a
GSK					Assay Description The ligand binding domain for PPAR was fused to the yeast transcription factor GAL4 DNA binding domain. CV-1 cells were transiently transfected with ...				J Med Chem 50: 685-95 (2007) Article DOI: 10.1021/jm058056x BindingDB Entry DOI: 10.7270/Q2RN3669
					More data for this Ligand-Target Pair