Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Acyl-CoA desaturase 1
(Mus musculus) | BDBM50445781
(CHEMBL3104612)Show SMILES Cc1nc(sc1C(=O)NCc1ccccc1)-c1noc(Cc2ccccc2)n1 Show InChI InChI=1S/C21H18N4O2S/c1-14-18(20(26)22-13-16-10-6-3-7-11-16)28-21(23-14)19-24-17(27-25-19)12-15-8-4-2-5-9-15/h2-11H,12-13H2,1H3,(H,22,26) | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 75 | n/a | n/a | n/a | n/a | n/a | n/a |
Xenon Pharmaceuticals Inc.
Curated by ChEMBL
| Assay Description
Inhibition of SCD1 in mouse liver microsomes |
Bioorg Med Chem Lett 24: 520-5 (2014)
Article DOI: 10.1016/j.bmcl.2013.12.036
BindingDB Entry DOI: 10.7270/Q2QJ7JRS |
More data for this
Ligand-Target Pair | |
Stearoyl-CoA desaturase
(Homo sapiens (Human)) | BDBM50445781
(CHEMBL3104612)Show SMILES Cc1nc(sc1C(=O)NCc1ccccc1)-c1noc(Cc2ccccc2)n1 Show InChI InChI=1S/C21H18N4O2S/c1-14-18(20(26)22-13-16-10-6-3-7-11-16)28-21(23-14)19-24-17(27-25-19)12-15-8-4-2-5-9-15/h2-11H,12-13H2,1H3,(H,22,26) | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.93E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Xenon Pharmaceuticals Inc.
Curated by ChEMBL
| Assay Description
Inhibition of SCD1 in human HepG2 cells using [1-14C]stearic acid as substrate |
Bioorg Med Chem Lett 24: 520-5 (2014)
Article DOI: 10.1016/j.bmcl.2013.12.036
BindingDB Entry DOI: 10.7270/Q2QJ7JRS |
More data for this
Ligand-Target Pair | |