Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Stearoyl-CoA desaturase
(Homo sapiens (Human)) | BDBM50445731
(CHEMBL3104392)Show SMILES Cc1nc(sc1C(=O)NCc1ccccc1)-n1ccc(OCCC2CC2)cc1=O Show InChI InChI=1S/C22H23N3O3S/c1-15-20(21(27)23-14-17-5-3-2-4-6-17)29-22(24-15)25-11-9-18(13-19(25)26)28-12-10-16-7-8-16/h2-6,9,11,13,16H,7-8,10,12,14H2,1H3,(H,23,27) | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
Xenon Pharmaceuticals Inc.
Curated by ChEMBL
| Assay Description
Inhibition of SCD1 in human HepG2 cells using radiolabeled stearic acid as substrate |
Bioorg Med Chem Lett 24: 526-31 (2014)
Article DOI: 10.1016/j.bmcl.2013.12.035
BindingDB Entry DOI: 10.7270/Q20003J1 |
More data for this
Ligand-Target Pair | |
Acyl-CoA desaturase 1
(Mus musculus) | BDBM50445731
(CHEMBL3104392)Show SMILES Cc1nc(sc1C(=O)NCc1ccccc1)-n1ccc(OCCC2CC2)cc1=O Show InChI InChI=1S/C22H23N3O3S/c1-15-20(21(27)23-14-17-5-3-2-4-6-17)29-22(24-15)25-11-9-18(13-19(25)26)28-12-10-16-7-8-16/h2-6,9,11,13,16H,7-8,10,12,14H2,1H3,(H,23,27) | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
Xenon Pharmaceuticals Inc.
Curated by ChEMBL
| Assay Description
Inhibition of SCD1 in mouse liver microsomes |
Bioorg Med Chem Lett 24: 526-31 (2014)
Article DOI: 10.1016/j.bmcl.2013.12.035
BindingDB Entry DOI: 10.7270/Q20003J1 |
More data for this
Ligand-Target Pair | |