Found 2 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Acyl-CoA desaturase 1
(Mus musculus) | BDBM50445736
(CHEMBL3104389)Show SMILES Cc1nc(sc1C(=O)NCc1ccccc1)-n1ccc(OCc2ccccc2)cc1=O Show InChI InChI=1S/C24H21N3O3S/c1-17-22(23(29)25-15-18-8-4-2-5-9-18)31-24(26-17)27-13-12-20(14-21(27)28)30-16-19-10-6-3-7-11-19/h2-14H,15-16H2,1H3,(H,25,29) | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 25 | n/a | n/a | n/a | n/a | n/a | n/a |
Xenon Pharmaceuticals Inc.
Curated by ChEMBL
| Assay Description Inhibition of SCD1 in mouse liver microsomes |
Bioorg Med Chem Lett 24: 526-31 (2014)
Article DOI: 10.1016/j.bmcl.2013.12.035 BindingDB Entry DOI: 10.7270/Q20003J1 |
More data for this Ligand-Target Pair | |
Stearoyl-CoA desaturase
(Homo sapiens (Human)) | BDBM50445736
(CHEMBL3104389)Show SMILES Cc1nc(sc1C(=O)NCc1ccccc1)-n1ccc(OCc2ccccc2)cc1=O Show InChI InChI=1S/C24H21N3O3S/c1-17-22(23(29)25-15-18-8-4-2-5-9-18)31-24(26-17)27-13-12-20(14-21(27)28)30-16-19-10-6-3-7-11-19/h2-14H,15-16H2,1H3,(H,25,29) | PDB
KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 26 | n/a | n/a | n/a | n/a | n/a | n/a |
Xenon Pharmaceuticals Inc.
Curated by ChEMBL
| Assay Description Inhibition of SCD1 in human HepG2 cells using radiolabeled stearic acid as substrate |
Bioorg Med Chem Lett 24: 526-31 (2014)
Article DOI: 10.1016/j.bmcl.2013.12.035 BindingDB Entry DOI: 10.7270/Q20003J1 |
More data for this Ligand-Target Pair | |