Found 2 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Acyl-CoA desaturase 1
(Mus musculus) | BDBM50060670
(CHEMBL3394692)Show SMILES Cc1nc(sc1C(=O)NCc1cccnc1)-n1cnn(CC2CC2)c1=O Show InChI InChI=1S/C17H18N6O2S/c1-11-14(15(24)19-8-13-3-2-6-18-7-13)26-16(21-11)22-10-20-23(17(22)25)9-12-4-5-12/h2-3,6-7,10,12H,4-5,8-9H2,1H3,(H,19,24) | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 98 | n/a | n/a | n/a | n/a | n/a | n/a |
Xenon Pharmaceuticals Inc.
Curated by ChEMBL
| Assay Description Inhibition of SCD1 in ICR mouse liver microsome using [9,10 3H]- stearoyl-Coenzyme A substrate assessed as decreased production of tritiated water af... |
Bioorg Med Chem 23: 455-65 (2015)
Article DOI: 10.1016/j.bmc.2014.12.014 BindingDB Entry DOI: 10.7270/Q2GM890X |
More data for this Ligand-Target Pair | |
Stearoyl-CoA desaturase
(Homo sapiens (Human)) | BDBM50060670
(CHEMBL3394692)Show SMILES Cc1nc(sc1C(=O)NCc1cccnc1)-n1cnn(CC2CC2)c1=O Show InChI InChI=1S/C17H18N6O2S/c1-11-14(15(24)19-8-13-3-2-6-18-7-13)26-16(21-11)22-10-20-23(17(22)25)9-12-4-5-12/h2-3,6-7,10,12H,4-5,8-9H2,1H3,(H,19,24) | PDB
KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 140 | n/a | n/a | n/a | n/a | n/a | n/a |
Xenon Pharmaceuticals Inc.
Curated by ChEMBL
| Assay Description Inhibition of SCD1 in human HepG2 cells using [14C]-stearate substrate assessed as decreased production of [14C]-oleic acid after 24 hrs |
Bioorg Med Chem 23: 455-65 (2015)
Article DOI: 10.1016/j.bmc.2014.12.014 BindingDB Entry DOI: 10.7270/Q2GM890X |
More data for this Ligand-Target Pair | |