Found 3 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Peroxisome proliferator-activated receptor alpha
(Homo sapiens (Human)) | BDBM50332465
(2-methyl-2-(2-methyl-4-((4-methyl-2-(4-(trifluorom...)Show SMILES Cc1nc(sc1C[Se]c1ccc(OC(C)(C)C(O)=O)c(C)c1)-c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C23H22F3NO3SSe/c1-13-11-17(9-10-18(13)30-22(3,4)21(28)29)32-12-19-14(2)27-20(31-19)15-5-7-16(8-6-15)23(24,25)26/h5-11H,12H2,1-4H3,(H,28,29) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 15.2 | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
Agonist activity at human PPAR-alpha expressed in african green monkey CV-1 cells after 24 hrs by luciferase reporter gene assay |
Bioorg Med Chem Lett 20: 7239-42 (2010)
Article DOI: 10.1016/j.bmcl.2010.10.103
BindingDB Entry DOI: 10.7270/Q2SN0975 |
More data for this
Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50332465
(2-methyl-2-(2-methyl-4-((4-methyl-2-(4-(trifluorom...)Show SMILES Cc1nc(sc1C[Se]c1ccc(OC(C)(C)C(O)=O)c(C)c1)-c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C23H22F3NO3SSe/c1-13-11-17(9-10-18(13)30-22(3,4)21(28)29)32-12-19-14(2)27-20(31-19)15-5-7-16(8-6-15)23(24,25)26/h5-11H,12H2,1-4H3,(H,28,29) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 100 | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
Agonist activity at human PPAR-gamma expressed in african green monkey CV-1 cells after 24 hrs by luciferase reporter gene assay |
Bioorg Med Chem Lett 20: 7239-42 (2010)
Article DOI: 10.1016/j.bmcl.2010.10.103
BindingDB Entry DOI: 10.7270/Q2SN0975 |
More data for this
Ligand-Target Pair | |
Peroxisome proliferator-activated receptor delta
(Homo sapiens (Human)) | BDBM50332465
(2-methyl-2-(2-methyl-4-((4-methyl-2-(4-(trifluorom...)Show SMILES Cc1nc(sc1C[Se]c1ccc(OC(C)(C)C(O)=O)c(C)c1)-c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C23H22F3NO3SSe/c1-13-11-17(9-10-18(13)30-22(3,4)21(28)29)32-12-19-14(2)27-20(31-19)15-5-7-16(8-6-15)23(24,25)26/h5-11H,12H2,1-4H3,(H,28,29) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 4.5 | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
Agonist activity at human PPAR-delta expressed in african green monkey CV-1 cells after 24 hrs by luciferase reporter gene assay |
Bioorg Med Chem Lett 20: 7239-42 (2010)
Article DOI: 10.1016/j.bmcl.2010.10.103
BindingDB Entry DOI: 10.7270/Q2SN0975 |
More data for this
Ligand-Target Pair | |