Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 397.4 BDBM474348

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Polymerase acidic protein ()	BDBM474348 ((S)-6-benzhydryl-11-hydroxy-2,3-dimethyl- 5H-imida...) Show SMILES Cc1nc2-c3c(O)c(=O)ccn3[C@H](Cn2c1C)C(c1ccccc1)c1ccccc1 |r| Show InChI InChI=1S/C25H23N3O2/c1-16-17(2)28-15-20(27-14-13-21(29)24(30)23(27)25(28)26-16)22(18-9-5-3-6-10-18)19-11-7-4-8-12-19/h3-14,20,22,30H,15H2,1-2H3/t20-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...				Citation and Details BindingDB Entry DOI: 10.7270/Q2Z60S8G
					More data for this Ligand-Target Pair
Polymerase acidic protein ()	BDBM474348 ((S)-6-benzhydryl-11-hydroxy-2,3-dimethyl- 5H-imida...) Show SMILES Cc1nc2-c3c(O)c(=O)ccn3[C@H](Cn2c1C)C(c1ccccc1)c1ccccc1 |r| Show InChI InChI=1S/C25H23N3O2/c1-16-17(2)28-15-20(27-14-13-21(29)24(30)23(27)25(28)26-16)22(18-9-5-3-6-10-18)19-11-7-4-8-12-19/h3-14,20,22,30H,15H2,1-2H3/t20-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...				US Patent US10858366 (2020) BindingDB Entry DOI: 10.7270/Q2KH0RDJ
					More data for this Ligand-Target Pair